What are the challenges of making the flu vaccine

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• What are the challenges of making the flu vaccine?

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• Why does it take so long?

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• What significant contributions might
  Biotechnology make to the process of making
  vaccines?

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• What is Biotechnology?

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Biotechnology

• The use of cellular and biomolecular processes to
  solve problems or make useful products.
• BIO (Biotechnology Industry Organization)

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MA Standards

• Biotechnology
• Biotechnology is a rapidly expanding field of
  biology that uses a growing set of techniques to
  derive valuable products from organisms and their
  cells. Biotechnology is already commonly used to
  identify potential suspects or exonerate persons
  wrongly accused of crimes, determine paternity,
  diagnose diseases, make high-yield pest-resistant
  crops, and treat genetic ailments. Educators
  should recognize the importance of introducing
  students to biotechnology so that they may better
  understand the molecular basis of heredity and
  critically evaluate the benefits and risks of
  this technology.

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• What is the connection between spiders and
  biotechnology?

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Transformation Animation DNA interactive (DNAi)
http//www.dnai.org Great source of information
about all things DNA. Has good animations as
well. To view animation on transformation,
click on "manipulation" at top menu, then on
"techniques", then transferring and sorting",
then "transformation"
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pGAL

• Contains gene for b galactosidase
• Contains gene for amplicillin resistance

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Transformation with pGAL

• b galactosidase cleaves artificial substrate to
  form a blue product
• Transformed colonies appear blue