The NIHR Clinical Research Network

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The NIHR Clinical Research Network

• Prof Tony Kendrick
• Co-Director HIOW CLRN
• Associate Dean for Clinical Research
• University of Southampton

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Strengthening the evidence base for prevention,
diagnosis, treatment and management of illness
and disease www.dh.gov.uk/publications
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Main reasons for change?

• Involve more health professionals in research
• Increase public involvement in research
• Co-ordinate research more effectively
• Make funding more transparent
• Reflect the needs of the NHS

Strengthening the evidence base for prevention,
diagnosis, treatment and management of illness
and disease in primary care www.dh.gov.uk/publicat
ions
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The structure of networks
TOPIC SPECIFIC CLINICAL RESEARCH NETWORKS
COMPREHENSIVE CLINICAL RESEARCH NETWORKS Hampshi
re Isle of Wight CLRN Peninsula CLRN Western
CLRN
Practices Patients
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The structure of networks
TOPIC SPECIFIC CLINICAL RESEARCH NETWORKS
COMPREHENSIVE CLINICAL RESEARCH NETWORKS Hampshi
re Isle of Wight CLRN Peninsula CLRN Western
CLRN
Practices Patients
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PCRN (SW)
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PCRN SOUTH WEST
West Hub PCRN South West Peninsula Medical
School (Primary Care) Smeall Building St Lukes
Campus Exeter EX1 2LU
North Hub PCRN South West South
Plaza Marlborough Street Bristol BS1 3NX
East Hub PCRN South West Primary Medical Care
University of Southampton Aldermoor Health
Centre Aldermoor Close Southampton SO16 5ST
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Potential benefits to Practices

• Answers clinically relevant questions and reduces
  practice/theory divide
• Patients do better in trials
• Trial new treatments
• Potential business opportunity?

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East Team
Dr Philip Evans (Director) Tel [phone]
E-Mail philip.evans_at_pms.ac.uk Dr Michael Moore
(Deputy Director) Tel [phone] E-Mail
mvm198_at_soton.ac.uk Rachel Exell (Network
Manager) Tel [phone] E-Mail
rachel.exell_at_pms.ac.uk Dr Jenny Baverstock
(Locality Manager) Tel [phone] E-Mail
jenny_at_soton.ac.uk Tricia Worby (Data Manager)
Tel [phone] E-Mail p.worby_at_soton.ac.uk
Megan Liddiard (Research Officer) Tel (023)
8024 1075 E-Mail m.liddiard_at_soton.ac.uk Jessica
Price (Research Officer PCRN MHRN)
Jessica.Price_at_hantspt-sw.nhs. Uk Jackie Seely
(Research Officer) Tel [phone] E-Mail
j.seely_at_soton.ac.uk Professor Tony Kendrick
(Academic Lead) Tel [phone] E-mail
A.R.Kendrick_at_soton.ac.uk
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The portfolio

• Trials and other high quality studies
• 233 on PCRN national portfolio
• Approximately 35 studies on PCRN(SW) portfolio
• A mix of
• Commercial v. non-commercial
• Interventional v. observational
• Home-grown v. Up the line !
• Wide ranging generalist areas from CBT to sore
  throat
• All depends on practice engagement

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Primary care cohorts and trials

• MRC DESCARTE decision rule support for severe
  symptoms and complications of acute red throat
• US Pharma (Investigator-led) GLOW global
  longitudinal registry of osteoporosis
• NIHR HTA PRISM primary care streptococcal
  management trial
• MRC/arc SCOOP trial of screening for
  osteoporosis

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What does the PCRN portfolio mean to you ?

• For commercial and non-commercial
• Kite-marked studies
• High quality
• Already peer-reviewed by GPs and academics
• Ethics/ Research Governance approved
• Relevant to NHS primary care
• Service support costs of undertaking research
  will come to practices (350k in Year 1 and
  rising)

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