Ontology Annotation Tree browser tool OAT

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Ontology Annotation Tree browser tool (OAT)
Getting started
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OAT - How to start a session
Click here to go to query page.
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OAT - Query form
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OAT Browsing (1)
First number tells you how many probe sets you
submitted. Second number tells you how many of
the probe sets were annotated to the
ontology. Following a hyperlinked number will
result in a list of the respective probe sets.
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OAT Browsing (2)
By pressing in front of a keyword, the
associated children of the term are displayed.
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OAT Browsing (3)
Let us look closer on a node in the ontology tree
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OAT Browsing (4)
The level of significance of an direct annotation
is given by the probability of that this
annotation occurs by chance.
This example from the MeSH tree illustrates that
Enzyme Induction have a low probability (1.3)
and is therefore significant, but Molecular
Sequence Data have a very high probability
(99,8) and should therefore be present in almost
every query of this magnitude.
NOTE The number of submitted probe sets affects
the probability more probes increase the chance
of an annotation.
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OAT Report (1)
Continue to expand and contract the nodes in the
tree, until a satisfying level of details is
reached. The next step is to summarize the
interesting parts in a report.
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OAT Report (2)
To make a report of the most interesting
keyword-annotations, just mark the checkboxes.
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OAT Report (3)
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OAT Report (4)
The elements of the Report-table
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OAT Further information
You can now consider yourself trained on the
OAT-tool. Enjoy it. Anders Bresell will gladly
answer any remaining question. (e.g. What data
is used?, I still doesnt get the part of
significance? or What programming language was
used? )
Any suggestions of improvements are also welcome.
E-mail anders.bresell_at_astrazeneca.com