Research and Education

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Research and Education
CANCeR

• Contact Peter F. Minke Ph.D.

Young Living Essential Oils 3125 West Executive
Parkway Lehi, Utah 84043
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Resources

• Young Life Research Clinic Institute of Natural
  Medicine
• Food and Drug Administration www.fda.gov
  (multiple sites)
• National Cancer Institute (NCI)
  http//cis.nci.nih.gov
• Office of Dietary Supplements (ODS)
  http//dietary-supplements.info.nih.gov/
• James A. Duke Ph.D databasears-grin.gov/duke/
• NAPRALERT database http//stneasy.cas.org

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Traditional Information

• Hartwell, J.L. (1969-1979)
• Plants Used Against Cancer. A Survey
• Lloydia 30-34
• A classic treatise on the reports of
  historical use of plants against cancer

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Cancer Research (Ponce School of Medicine)

• Academic collaboration with Young Living
  Essential Oils
• Investigation of the anti-cancer activity of
  essential oil of frankincense
• Investigation of the effects of various essential
  oils on cellular DNA repair

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In Vitro Effects of Frankincense on Cancer Cells

• In vitro growth inhibition assay cancer cells
  (breast cancer cell line MCF-7) growing in
  culture conditions are introduced to various
  concentrations of frankincense essential oil for
  24 hrs. and growth inhibition is measured by
  evaluating cell proliferation.
• The results (repeatable) are biphasic showing
  either an inhibition or stimulation of cell
  proliferation depending on the concentration of
  frankincense oil in the growth media.
• Maximal growth inhibition occurs at 50 mg/ml
  (65 average reduction in cell number) and 200
  mg/ml (40 average reduction in cell number) of
  frankincense oil in culture media.
• Growth stimulation (less than 10 average
  increase in cell number) occurs at 100 mg/ml.
• Flow cytometry studies to evaluate the cause of
  cell number reduction (by necrosis or by
  apoptosis) are inconclusive.
• Next steps for Young Living Essential Oils
  Clinical studies in which frankincense oil is
  administered in repeated small doses to achieve a
  low sustained physiological concentration in the
  target tissue are in the planning stages.

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Essential Oils and DNA Repair

• The ability of cells to repair damage to DNA
  caused by toxins, radiation, or other stressors
  is vital to the health of the individual.
• DNA repair in cultured lymphocytes has been shown
  to decrease with the age of the donor and is
  dramatically reduced in people with cancer.
• Efforts have begun to screen essential oils for
  effects on DNA repair in cultured lymphocytes.
  This work has the potential to link essential
  oils with health and longevity at a molecular and
  cellular level.

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Current Research

• Bioassay Analyses to Determine Anti-Cancer
  Activity of Essential Oils. Nicole A. Stevens,
  Masters Thesis, Brigham Young University.
  August 2002
• Essential oils and support for research provided
  by Young Living Essential Oils
• Anti-cancer activity (cancer cell toxicity) was
  evaluated for 74 essential oils using four cancer
  cell lines (breast, cervical, prostate, skin) and
  a control cell line

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Key Findings-N.A.Stevens

• 26 of the 44 active oils (59) are
  cancer-specific and should be considered for
  further study
• These essential oils that have been used
  medicinally for centuries may prove to be a very
  valuable resource in our search for new cancer
  drugs

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Current Research (Sabinsa)

• Young Living scientists engaged in professional
  collaborations with Sabinsa Corporation
  scientists (see Sabinsa poster on Selenium)
• FDA recognition of selenium for prevention and
  treatment of cancer (limited health claim)
• Selenium is an ingredient in ImmuPro

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Disclaimer

• This poster was presented and written for the
  sole purpose of providing educational and
  research information on cancer. It is not
  designed, in whole or in part, as advice for
  self-diagnosis or self-treatment and should not
  be construed as such. Young Living does not
  promote or endorse the treatment of cancer with
  Young Living products.

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