Reparative processes and cellular adaptations

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Reparative processes and cellular adaptations
SYLLABUS RBP(Robbins Basic Pathology)
Chapter Cell Injury, Adaptation, and
Death Hypertrophy Hyperplasia Metaplasia Tissue
Repair Cell Regeneration and Fibrosis (all)
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Reparative processes and cellular adaptations

• 48-I Granulation tissue
• 48 Foreign body granuloma
• 44 Myocardial hypertrophy
• 192 Benign prostatic hyperplasia (BPH)
• 287 Columnar to squamous bronchial metaplasia

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Granulation tissue

• proliferating small blood vessels
• proliferating fibroblasts
• macrophages
• - other inflammatory cells
• other cellular elements of connective tissue
• non numerous connective tissue fibers

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Granulation tissue
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Granulation tissue
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Foreign body granuloma
foreign-body type giant cells epithelioid
cells other elements of granulation tissue
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Foreign body granuloma
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Foreign body granuloma
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Foreign-body type giant cells (framed
white) Langhans cells (framed blue)
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Myocardial hypertrophy
enlarged myocardial cells
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Myocardial hypertrophy
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Myocardial hypertrophy
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Benign prostatic hyperplasia (BPH)
nodularity due to - glandular proliferation or
dilation- fibrous and muscular proliferation of
the stroma - foci of squamous metaplasia -
small areas of infarction - papillary buds and
infoldings of epithelium
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Benign prostatic hyperplasia (BPH)
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Benign prostatic hyperplasia (BPH)
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Benign prostatic hyperplasia (BPH)
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Columnar to squamous bronchial metaplasia
normal ciliated columnar epithelial cells of the
bronchi replaced focally or widely by stratified
squamous epithelium
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Columnar to squamous bronchial metaplasia
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Columnar to squamous bronchial metaplasia