Introduction to

1

• Introduction to
• Computational and
• Mathematical
• Biology
• Lecture 5B
• Dr. Eduardo Mendoza
• Mathematics Department Physics
  Department
• University of the Philippines
  Ludwig-Maximilians-University
• Diliman Munich, Germany
• eduardom_at_math.upd.edu.ph
  Eduardo.Mendoza_at_physik.uni-muenchen.de

2
Topics to be covered

• Phylogenetics (contd)
• Character Based Methods (contd)
• Weighted Parsimony and Sankoffs Algorithm
• Large Parsimony Problem
• Branch and Bound, Nearest Neighbor Interchanges
  (NNI)
• Compatibility and Parsimony
• Perfect Phylogeny-Large Compatibility Problem
• Distance-Based Methods
• Pairwise Distances
• Protein (PAM) and DNA (Jukes-Cantor) distances
• Least Squares Methods
• UPGMA
• Neighbor Joining
• Remarks

3
(No Transcript)