Orthomyxoviridae: human influenza viruses

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Orthomyxoviridae human influenza viruses
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Poxviridae
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Retroviridae HIV
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Enveloped viruses versusmembrane-containing
viruses
Alphaviruses Flaviviruses
PRD1
HSV / f6
PM2 ?
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Bacteriophage PRD1
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penton
outer leaflet
DNA
inner leaflet
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PRD1 structural proteins
P3 major coat 43 kDa
x P30 minor coat 9 kDa
x P2 receptor binding 64 kDa P5
spike 34 kDa P31 penton
14 kDa x

CAPSID
VERTICES
P6 portal 18 kDa
P9 packaging ATPase 26 kDa P20
DNA packaging (M) 5 kDa P22 DNA packaging
(M) 6 kDa
PACKAGING VERTEX
P7 transglycosylase (M) 27 kDa P14
DNA delivery (M) 15 kDa P15 muramidase
17 kDa P16 infectivity (M)
13 kDa x
P18 DNA delivery (M) 10 kDa P32
DNA delivery (M) 5 kDa P34 (M)
7 kDa
ENTRY
(M) integral membrane protein
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Sarah Butcher
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David Stuart Nicoal Abrescia
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Richard Kuhn
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John Briggs Retroviruses
Asymmetric Variable in diameter Envelopment
requires both viral and cellular
proteins Membrane plays role in both assembly
and maturation
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George J Thomas
Escherichia coli
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George J. Thomas
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irido
adeno
PRD1
Lineage 1 Lineage 2 Lineage 3
phi6
BTV
herpes