Complete Chapter 8 Test (4B)

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Class Topics
Title Biology 3/7/07
Objectives

• To assess learning about Chapter 8.

• Complete Chapter 8 Test (4B)
• Inbreeding article
• Notes Chapter 9
• "Whenever you are asked if you can do a job, tell
  'em, 'Certainly I can!' Then get busy and find
  out how to do it."
• Theodore Roosevelt

Sunday, August 09, 2015 529 PM
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Class Assignments
By When
What

• Read 207-214 3/7/07
• W.S. 9.1 3/9/07
• Chapter 9 Quiz 1 3/13/07
• Due this class period
• Due next class period
• Due in the future

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Grade Sheet
2A p. 157 (5 pts.)
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Review Magazine article Go ahead and kiss your
cousin

• Why are neural degenerative diseases 8 times more
  common in Bradford than the rest of the UK? (62)
• What are lethal alleles (62)?
• Why is it likely that 80 of marriages in history
  were between 2nd cousins or closer? (62)
• Why would some rich families encourage cousin
  marriages? (63)
• Why do some cases of inbreeding lead to many
  diseases while others do not? (63)
• What is outbreeding? (64)
• What are some problems with outbreeding? (64)

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Johann Friedrich Miescher

• 1868 - first scientist to isolate DNA
• Studied pus from wounds
• Called DNA - nuclein
• Accomplishment not acknowledged at the time

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Frederick Griffith

• working on vaccine for pneumonia (1928)
• Strains
• Smooth (IIIS) - virulent
• Rough (IIR) - avirulent

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Graphic taken from the MIT Hypertext
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From http//ribonode.ucsc.edu/HuGen/01_80H/01_80H
lec6.html
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Transformation

• Something changed the IIR strain to the IIIS
  strain. What was it?
• Transformation is the process of changing one
  form of bacteria into another form
• trading genetic information
• Between dead (HKIIIS) and living IIR

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Griffiths experiment

• Problem
• Hypothesis
• Procedure
• Conclusion
• Transformation

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Historical Perspective

• Genetic material
• Believed to be protein
• More complex than nucleic acids
• More common than nucleic acids

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Avery and Co.McCarty MacLeod

• 1944 - took Griffiths experiment one step
  farther
• found out what had caused transformation
• Used enzymes to breakdown organic molecules -
  Carbohydrase, Protease, Ribonuclease, and
  Deoxyribonuclease

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Averys conclusion

• Lipase didnt block transformation
• Carbohydrase didnt block transformation
• Protease didnt block Transformation
• Ribonuclease didnt block transformation
• Deoxyribonuclease blocked transformation
• Whats the conclusion?
• DNA is the genetic material of bacteria

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Averys experiment

• Problem
• Hypothesis
• Procedure
• Conclusion

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From http//ribonode.ucsc.edu/HuGen/01_80H/01_80H
lec6.html