Epidemiology of ulcerative colitis - PowerPoint PPT Presentation

1 / 9
About This Presentation
Title:

Epidemiology of ulcerative colitis

Description:

Epidemiology of ulcerative colitis – PowerPoint PPT presentation

Number of Views:96
Avg rating:3.0/5.0
Slides: 10
Provided by: a1554
Category:

less

Transcript and Presenter's Notes

Title: Epidemiology of ulcerative colitis


1
Epidemiology of ulcerative colitis
  • First description from India
  • 1939- Chopra and Ray, School of Tropical Medicine
    Calcutta, 120 cases of nonspecific colitis
  • Later descriptions
  • Year Author No. of cases
  • 1954 Chaudhari et al -
  • 1962 Gadekar et al -
  • 1965 Tandon et al 69
  • 1967 Wakeel et al 57
  • Chuttani et al 46
  • 1985 Khosla et al 10
  • 1986 Kapur et al 40
  • 1991 Kochhar et al 150
  • 1997 Habeeb et al -
  • 2001 Sood et al 145
  • Indian Medical Gazette

2
Epidemiology of ulcerative colitis
  • Incidence
  • India West
  • Case series Population studies
  • Data sketchy Complete
  • Number small Large series
  • Limited variables considered Multiple variables
    analyzed

Hospital incidence per 100,000 population 1965
Tandon et al Delhi 34.7 1967 Chuttani et al
Bombay 26.1 1967 Chuttani et al Ahmedabad 3.6
Prevalence in the community India (Khosla et al,
Rohtak) 47.8/105 Norway 12.8/105 California
10.9/105 S. Europe 2/105 S. Africa
6.3/105 Japan 0.5/105
India gt USA/NorwaygtEuropegtJapan (India
overestimation due to improper diagnostic
criteria)
3
Epidemiology of ulcerative colitis
Age India Vs West India 20-40 yrs West 15-30
yrs 2nd peak at 60-80 yrs (west), not seen in
India Author Mean (yrs) Range (yrs) Sood et
al Ludhiana 31.7 14-65 Khosla et al Rohtak 24.4
(M) 38.0 (F) - Kapur P et al Delhi
- 13-65 Kochhar et al PGI - 13-78 Chuttani et
al MAMC 31.5 (M), 25.3 (F) 9-56
Patients in India present later most patients in
3rd, 4th decade
4
Epidemiology of ulcerative colitis
  • Gender
  • MF
  • Chuttani et al Delhi 2.31
  • Tandon et al Delhi 1.51
  • Khosla et al Rohtak 11
  • Kapur et al Delhi 11.2
  • Kochhar et al PGI 1.11
  • Sood et al Ludhiana 11.1

India Vs West India MF, MgtF West MF
Earlier studies MgtF Later studies MF (??
reporting in males )
5
Epidemiology of ulcerative colitis
  • Socioeconomic status, rural/urban, and smoking
  • Socioeconomic status
  • India Majority Lower socioeconomic status
  • West Majority Upper socioeconomic status
  • Rural /urban
  • India No data
  • West Urbangtrural
  • Smoking
  • India No data
  • West ? risk (40 less)
  • ? severity
  • ? hospitalization

Chuttani et al, Khosla et al, Sonnenberg A et al,
Calkins B M et al
6
Epidemiology of ulcerative colitis
Extra-intestinal manifestations PGI PGI
Mumbai WEST Kochhar et al Sethi et al Vakil
et al (1991) (2003) Arthralgia
10.7 10 21 10 Sacroileitis 14 16 0 10 Muc
ocutaneous lesions 2.7 2 1.7 10 Ocular
lesions 8 8 0 10 Hepatobiliary
1.3 2 3.4 5 Venous thrombosis 2 2 0 -
7
Epidemiology of ulcerative colitis
  • The BHU experience
  • Year GE Unit Hospital
  • New Cases
  • 1977 22 (41 / 104) 43 (0.8 / 104)
  • 2002 58 (21 / 104) 76 (1.3 / 104)
  • Total Cases
  • 1977 54 (112 / 104) -
  • 2002 187 ( 67 / 104) -

8
Epidemiology of ulcerative colitis
  • Prevalence / 100,000 population
  • India 45
  • UK Immigrant Indians 84
  • British Population 38 (32 - 98)
  • USA 42 (35 - 95)

9
Epidemiology of ulcerative colitis
  • Associated diseases
  • Tuberculosis (7 4 Pulmonary, 3 Intestinal)
  • Enteric Infections (Parasitic, Bacterial
    Viral)
  • - Likely Cause of Relapse in 1/3
  • (E coli 22, Aeromonas 5 Pseudom 3
    Salm 3)
  • Others (PSC, Thyroid etc.)

Tropical Gastroenterology 1995
Write a Comment
User Comments (0)
About PowerShow.com