Equine Parasites and The Health of Your Horse

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Equine ParasitesandThe Health of Your Horse
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Keys to Equine Health Care

• Nutrition Dental Care
• Vaccination Disease Prevention
• Pasture Stable Management
• Hoof care
• Parasite Control

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Parasite Control

• Internal Parasites An Overview
• Traditional Parasite Control
• New Concerns
• A New Approach
• Moxidectin

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Key Equine Parasites

• Large Strongyles (bloodworms)
• Small Strongyles (cyathostomes)
• Ascarids (large roundworms)

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Parasites of Secondary Importance

• Bots
• Pinworms
• Tapeworms

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Other Equine Parasites

• Threadworms
• Stomach worms
• Ligament worms
• Stomach hair worms
• Lungworms

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Traditional Parasite Control

• Large strongyles most damaging
• Migrating larvae damage cranial mesenteric
  artery and other tissues
• Often associated with colic

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Traditional Parasite Control

• Traditional control programs
• Focused on large strongyles
• Treatment intervals of 4-8 weeks
• Pasture sanitation

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New Concerns Small Strongyles

• Small strongyles Cyathostomes
• Encysted larval forms
• new pathogenic significance
• previously overshadowed by large strongyles

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New Concerns Small Strongyles

• Encysted larval forms
• Cyst wall forms protective barrier
• Very slow metabolic rate
• Resistant to conventional dewormers

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New Concerns Small Strongyles

• Larvae exiting cysts cause
• Colic
• Diarrhea
• Fever

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Moxidectin

• New generation of dewormer
• The answer to
• encysted small strongyle control
• AND
• traditional parasite problems

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Moxidectin Not a Clone
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Moxidectin

• The first equine dewormer with activity against
  encysted small strongyles (cyathostomes)
• Full parasitic life cycle control

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The Old Approach

• Control of
• Adult worms which are already programmed to
  die
• Larvae which have already done their greatest
  damage.

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The New Approach

• QUEST Gel eliminates
• migrating strongyle larvae
• adult strongyles
• and
• encysted cyathostome larvae

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The New Approach

• Longer-lasting parasite control
• New treatment Interval
• Every 3 months
• 3 Times per Year (Most of Canada)

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The New Approach

• Unique chemistry
• Unique gel formulation
• New Sure-Dial syringe
• Unique results

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New Treatment Interval
ivermectin
moxidectin
Days to egg reappearance
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Is Quest Gel safe?
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Moxidectin Toxicity Trials

• University Studies
• 2X, 3X, and 5X overdose for multiple consecutive
  days
• Only suckling foals got sick
• All survived
• 4-month label restriction

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Moxidectin safety

• gt5 years in 18 other countries
• gt6 million doses used
• Extensive toxicity data
• lt0.02 Adverse Reaction rate- lower now

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About the Rumors

• Internet - Have you heard?
• Miniature horse overdoses
• Dog dose of moxidectin is 3mcg/kg (400mcg/kg in
  the horse)
• New product close scrutiny
• Post-anthelmintic colic

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Post-anthelmintic colic

• Adult large strongyle lethality
• Gut inflammation edema
• Protein loss in the bowel
• Ascarid impaction Young horses only

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Diarrhea

• Gut edema
• Protein loss
• Bacterial colitis
• Salmonella or Clostridium
• Laminitis may result
• Other causes--antibiotics, stress, surgery,
  travel, etc

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Wormer Wars

• After they exit the cyst
• Kills more species
• Are they a threat today?
• Science or regulatory?
• Early bot stages
• Treatment interval

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• . . . a new generation of equine parasite control

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. . . Egg reappearance suppressed 84 days

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. . . only 3 doses per year
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. . . unique activity against encysted small
strongyles (cyathostomes)
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unique gel formulation
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Contact us! Wyeth Animal Health 1-800-267-1777