Dissecting working memory using functional MRI

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PHYSIOLOGICAL
LESION
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Inference from Lesion vs. Physiological
Studies Physiological methods reveal active
areas during task performance --
Sufficiency argument Lesion studies can assess
functional relevance by asking if behavior is
affected if neural activity in that area is
disrupted -- Necessary argument
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Brocas aphasia
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Transcranial Magnetic Stimulation (TMS)
method for non-invasive stimulation of
cerebral cortex trigger current flow through
coil generate magnetic field over
cortex. cause massive firing of neurons in
underlying cortex.
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Transcranial Magnetic Stimulation (TMS)
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Transcranial Magnetic Stimulation (TMS)
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Transcranial Magnetic Stimulation (TMS)
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Transcranial Magnetic Stimulation (TMS)
Demonstration
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PHYSIOLOGICAL
LESION
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CUE
DELAY
RESPONSE



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Single neuron recording
Population recording
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Event-Related Potentials (ERP)
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Event-Related Potentials (ERP)
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Electrocorticography (ECoG)
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Magnetoencephalography (MEG)
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Magnetoencephalography (MEG)
Sensing Coil Array 64 to 275 Sensing Locations
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Magnetoencephalography (MEG)
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