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HodgkinHuxley Theory of Nerve Membranes:

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Hodgkin-Huxley Theory of Nerve Membranes: FitzHugh-Nagumo Model. Basic Mathematical Model ... V is potential; INa, IK and IL are respectively the sodium, ... – PowerPoint PPT presentation

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Title: HodgkinHuxley Theory of Nerve Membranes:


1
Hodgkin-Huxley Theory of Nerve Membranes
  • FitzHugh-Nagumo Model

2
Basic Mathematical Model
3
Physical Equivalent Circuit
4
Equations
V is potential INa, IK and IL are respectively
the sodium, potassium and leakage currents. The
gs are constant conductances. VNa, VK and VL are
constant equilibrium potentials. The m, n and h
are variables, bounded by 0 and 1.
5
More Equations
6
FitzHugh-Nagumo Model
  • The time scales for m, n, h are not all of the
    same order
  • The time scales for m, h are much faster
  • Setting m, h to constants will still retain many
    features of the system
  • This results in a 2 variable model in V and n

7
The New 2 Variable System
  • Dimensionless
  • v is like V, w plays the role of m, n and h
  • 0ltalt1, b and g are positive constants

8
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