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PREVENTION OF CORONARY ARTERY DISEASE IN WOMEN

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Title: PREVENTION OF CORONARY ARTERY DISEASE IN WOMEN


1
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?? 50-59 15 6 60-69 22
9 70-79 39 16 80-89 43 17
Chart adapted from Barry, MJ, 2001, Early
Detection of Prostate Cancer
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16
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    80-90 ??????? ?????????? ????????? ? ??????????
    ???????????? ?????????? 90
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    ??????? ?????????????? ?????? ? ???????????
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    ?????????? ???????????? 20-30

17
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??? ????? ?? ??????? ???????
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?????? ???????? ???
Thompson, Recent Advances in Prostate Cancer
18
To screen or not to screen?To treat or not to
treat????????? ??????????
  • Gleason 2-4 4-7 ???? ?????? ?? ???
  • Gleason 6 18-30 ???? ?????? ?? ???
  • Gleason 8-10 60-80 ???? ?????? ?? ???

Frankel et al. Lancet, 361 1122, March
2003 Albertsen et al., JAMA, 280 975, 1998
19
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    ? ??????????? ???? ?????? ?? 20

Schröder FH, Hugosson J, Roobol M J and all.N
Engl J Med (The New England journal of medicine)
2009 Mar 26360(13)1320-8.Screening and
prostate-cancer mortality in a randomized
European study.
24
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25
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??????????? ??????? 1978-2008
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    1000 ? ??? (???????), ?. ?. ??? ? 4 ????
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    ???????????? ??? ??????? ???????? (??????????
    ??????????, ????????? ?????) ? ???????? ????????
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34
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  • Detection of prostate cancer is like picking
    your nose in publicYou have to know what you are
    going to do if you find something
  • Ian Tannock MD,PHD.Princess Margaret Hospital,
    Canada

35
???????? ??? ????????? ??????
  • ?????? ??? ?????????????? ?????? ??? ??? ?????
    ??? ?????????? ? ???? ?? ??????? ?????? ?????,
    ??? ?????? ??????, ???? ???-?????? ???????Ian
    Tannock MD,PHD.Princess Margaret Hospital, Canada

36
???-???????? ????????? ?????? ? ???
  • 13/05/2002 John Doe and Mary Doe ????????
    ???????? ??? ?? 400,000 ?????? Dr. Roe and Roe
    Medical Center
  • 62-?????? ??????? ????????? ? ????? 17/11/95
    (??? 4,1), 6/01/97 (??? 4,8), 2/12/97 (??? 4,5).
    ??? ?????????? ???????????? ??? ?????????,
    ?????????????? ???????????? ?? ???????????. ?
    ???? 2000 ??? ??? 10,2 ??????????? ???????,
    ????????????? ?????????????????????? ???.
    ??????? (??????????????, ??????????????, ???????
    ???????) ??????? ? ??????????? ?????????? ?
    ??????????? ????????? .

37
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  • 11/09/06 58-?????? ??????? ?. ????????? ?
    ??????? ? ???? ?? ??????????? ??????????. ???
    6,4.(???? 1, ?????????).15/02/08 ?????????
    ???????? ???? 1, ???????. ??? ?? ????. ???
    5/06/08 17,3, 10/06/08 5,5. ??????????????
    ???????????? ?? ?????????. 20/03/09 ??????
    ?????? ?? ??? ?????????????? ?????? .????????? ?
    ????. ??? 27/03/09 74,4, ??? ?????????????? ???
    ???????? ?????? 7 ? ?????????????? ????????,
    ????????? ? ??????????? ????????? ?? ???,
    ????????? ? ?????? ?? ???. 18/05/09 ?????????????
    ????????????. 5-?????? ???????????? ? ????
    ?????? ????? 20-30.

38
???????????????? ??????????? ??? - ????
Catalona WJ, Partin AW, Slawin KM, et al. Use of
the percentage of free prostate-specific antigen
to enhance differentiation of prostate cancer
from benign prostatic disease a prospective
multi-center clinical trial. JAMA 279 1542-7,
1998
39
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40
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