Microbiology: A Systems Approach, 2nd ed'

1
Microbiology A Systems Approach, 2nd ed.

• Chapter 21 Infectious Diseases Affecting the
  Respiratory System

2
21.4 Diseases Caused by Microorganisms Affecting
the Upper and Lower Respiratory Tract

• A number of infectious agents affect both the
  upper and lower respiratory tract regions
• Most well-known whopping cough, respiratory
  syncytial virus (RSV), and influenza

3
Fungal diseases

• Histoplasmosis
• Coccidioidomycosis
• Blastomycosis
• Pneumocystis Pneumonia

4
Histoplasmosis

• Histoplasma capsulatum, dimorphic fungus

Figure 24.17
5
Histoplasmosis

• Transmitted by airborne conidia from soil
• Diagnosis by culturing fungus
• Treatment Amphotericin B

Figure 24.18
6
Coccidioidomycosis

• Coccidioides immitis

Figure 24.19
7
Coccidioidomycosis

• Transmitted by airborne arthrospores
• Diagnosis by serological tests or DNA probe
• Treatment Amphotericin B

Figure 24.20
8
Blastomycosis

• Blastomyces dermatitidis, dimorphic fungus
• Found in soil
• Can cause extensive tissue destruction.
• Treatment Amphotericin B

9
Pneumocystis Pneumonia

• Pneumocystis jiroveci (P. carinii) is found in
  healthy human lungs.
• Pneumonia occurs in newly infected infants and
  immunosuppressed individuals.
• Treatment Timethoprim-sulfamethoxazole

Figure 24.22a
10
Pneumocystis
Figure 24.21