The Heart

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The Heart

• Major Topics for Discussion
• Myocardial infarction
• Complications of MI
• Aneurysm
• Rupture - hemopericardium
• Hypertensive heart disease
• Endocarditis (bacterial and nonbacterial)
• Neoplasia

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?
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Myocardial Infarction
What causes this?
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Atherosclerosis
What causes this?
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Coronary artery atherosclerosis
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Pathogenesis of Heart Attack
Region of Atherosclerosis
Thrombus
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Infarction (Death) of Human Heart Muscle
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Myocardial Infarction Leads to Acute
Inflammation
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Healing by Collagen Scar Tissue Formation
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Acute inflammatory cells arrive in the affected
heart muscle 24 hours following infarction
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Ventricular Aneurysm
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Hemopericardium and Cardiac Tamponade
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Pericardial Sac Filled with Blood Following
Rupture of Heart Wall
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Hypertensive Heart Disease
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Valvular Heart Disease

• Rheumatic Fever
• Bacterial Endocarditis
• Non-Bacterial (Marantic) Endocarditis
• Calcific Aortic Stenosis

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Pathogenesis of rheumatic fever.
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Chronic Rheumatic Valvulitis
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Chronic Rheumatic Valvulitis
Note Fish Mouth Appearance of Mitral Valve
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Valve Destruction in Bacterial Endocarditis
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Non-Bacterial (Marantic) Endocarditis
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Calcified Congenital Bicuspid Aortic Valve
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Lymphocytes in heart of patient with viral
myocarditis..
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Fibrinous Pericaditis
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Constrictive Pericarditis
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Atrial Myxoma.
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Key Points

• Atherosclerosis is a chronic disease affecting
  small and medium-sized arteries.
• Risk factors include diet, lack of exercise,
  smoking, and diabetes (high blood sugar).
• Complications include heart attack, stroke, and
  abdominal aneurysm.

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Path Key Words

• Aneurysm
• Angina pectoralis
• Arrhythmia
• Atheromatous plaque
• Berry aneurysm
• Complication of atherosclerosis
• Cor pulmonale
• Dissecting aortic aneurysm

• Endocarditis
• Fatty streak
• Fibrinoid necrosis of arterioles
• Hyaline arteriosclerosis
• Rheumatic fever
• Risk factors for atherosclerosis
• Varicose veins