Pr

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A database of modules present in microbial
proteomes
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Evolution of E. coli paralogous proteins

• Biological concept
• Homologous modules in E. coli

• Aims
• Finding out all modules
• Grouping homologous modules
• in families

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Evolution of E. coli paralogous proteins

• Biological concept
• Homologous modules in E. coli

• Aims
• Finding out all modules
• Grouping homologous modules
• in families

• Needs
• Storing the data
• Querying

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Evolution of E. coli paralogous proteins

• Biological concept
• Homologous modules in E. coli

• Database
• Database Schema
• DataBase Management
• System File Maker Pro

• Aims
• Finding out all modules
• Grouping homologous modules
• in families

• Web Site
• www-colipage.igmors.u-psud.fr

• Needs
• Storing the data
• Querying

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Now ?
How to go from one genome to several genomes ?
Needs

• Biological concept
• Homologous modules

• Aims
• Finding out all modules
• Grouping homologous modules
• in families

• Asking
• very expressive queries

• Providing
• graphical representation

• Measuring evolutionary
• distance separating species

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We want to deal with
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