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CCF and Aging

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Ace Inhibitors (A2 receptor antagonists) Specific Treatment of ... Ace Inhibitors (A2 receptor antagonists) Beta Blockers. Digoxin. Spironolactone. Vasodilators ... – PowerPoint PPT presentation

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Title: CCF and Aging


1
CCF and Aging
  • John Puxty
  • puxtyj_at_post.queensu.ca

2
Issues to consider
  • Diagnosis may be delayed
  • Many of the studies with B blocker, ACIs and
    vasodilators in ambulatory setting with gradual
    dose adjustment
  • Confounding co-morbidities both cardiac and
    non-cardiac
  • Diastolic dysfunction common so do not treat only
    cosmetic finding
  • Underuse of diagnostic proceedures and effective
    Txs

3
The Aging Heart
4
Cardiac Output and Age
5
Heart Rate and Age
6
Presentation Of CCF
  • Prevalence of 10 80 years group
  • Often atypical weakness, fatigue, weight loss,
    confusion
  • Often associated with pneumonia, AF, Thyroid
    disease, Renal Disease
  • Medication usage often factor in precipitation
  • 50 have normal LVEV (diastolic dysfunction)

7
General Management Measures
  • Fluid and Na restriction
  • Regular physical activity
  • Review medications Alcohol, NSAIs
  • Manage Hypertension and IHD appropriately
  • Treat exacerbating factors anemia, thyroid
    disease, obesity, arryhthmias, infection

8
Specific Treatment of CCF
  • Diuretics

9
Specific Treatment of CCF
  • Diuretics
  • Ace Inhibitors (A2 receptor antagonists)

10
Specific Treatment of CCF
  • Diuretics
  • Ace Inhibitors (A2 receptor antagonists)
  • Beta Blockers carvedilol (3.125 mg bid 25 mg
    bid, Metoprolol 12.5 mg bid 50 mg bid)

11
Specific Treatment of CCF
  • Diuretics
  • Ace Inhibitors (A2 receptor antagonists)
  • Beta Blockers
  • Digoxin (nb NOT with normal LVEF and Sinus rhythm)

12
Specific Treatment of CCF
  • Diuretics
  • Ace Inhibitors (A2 receptor antagonists)
  • Beta Blockers
  • Digoxin
  • Spironolactone

13
Specific Treatment of CCF
  • Diuretics
  • Ace Inhibitors (A2 receptor antagonists)
  • Beta Blockers
  • Digoxin
  • Spironolactone
  • Vasodilators Isosorbide (10 mg tid-40 mg tid)
    and Hydralazine 10 mg tid 100 mg tid)

14
Specific Treatment of CCF
  • Diuretics
  • Ace Inhibitors (A2 receptor antagonists)
  • Beta Blockers
  • Digoxin
  • Spironolactone
  • Vasodilators
  • Calcium Channel Blockers (If normal LVEF!)
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