Biochemistry 6/e

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Nucleotide metabolism
Chem 454 Biochemistry II University of
Wisconsin-Eau Claire
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2 ATP-Grasp domains
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Generic Mechanism ATP-grasp domains (nucleotide
syntheses too)
http//cathwww.biochem.ucl.ac.uk/cgi-bin/cath/Goto
Cath.pl?cath3.30.1490.20
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To start off
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Ribonucleotide Reductase
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to Tyr .
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Suicide Inhibition
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Pyrimidine regulation
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Purine regulation
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Purine Degradation
GENE THERAPY!!
The Gout James Gillray(1757-1815), artist