Intravascular Ultrasound for Plaque Characterization

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Intravascular Ultrasound for Plaque
Characterization

• Scott R. Smith
• Boston Scientific Corporation
• The 3rd Vulnerable Plaque Symposium
• March 16, 2002

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Who needs interventional diagnosis and treatment?
Summary of National Heart, Lung, and Blood
Institute Workshop on Cardiovascular Risk
Assessment
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Diagnosis of Vulnerable Plaqueselecting a
population
Total 100 at risk 10 treated
14 saved 9 unnecessary 5 missed 1
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Plaque Structure
Courtesy of Dr. Renu Virmani Armed Forces
Institute of Pathology
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IVUS Plaque Imaging
Ruptured plaque
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Boston Scientific Imaging Systems
Atlantis? SR Plus Catheter
Galaxy? IVUS System

• Features Intended Benefits
• Tapered tip 2.5 Fr. Crossing Profile
• High definition 40MHz IVUS catheter.
• 6F Guide Catheter Compatibility.

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Galaxy? System Features and Intended Benefits

• Time-Saving Features
• Image Bookmarking
• LongView longitudinal measurements
• Pullback sled
• Enhanced Ease of Use
• TraceAssist automatic lumen trace function
• Angiographic compatibility
• Push button control

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Galaxy? System Research Capabilities

• Expanded Functionality
• Digital image storage
• Patient database
• Pre/post intervention analysis.
• RF Output
• Direct Access to RF signal for acquisition and
  analysis
• Future plans may include direct RF signal
  acquisition

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Imaging vs. Analysis
RF
Rectified and Log compressed
Low passed filtered - 10MHz
One image vector
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Other Imaging Modalities

• Independence
• Spatial resolution
• Contrast

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Conclusion

• Intravascular Ultrasound currently widely used
  for intravascular imaging
• Broad potential for plaque volume measurement and
  tissue characterization
• Variety of research efforts aimed at improving
  tissue contrast and resolution
• Thanks to
• Tat Jin Teo, PhD - BSC Imaging
• Renu Virmani, MD - AFIP
• Jay Kokate, PhD - BSC Applied Research