Metabolic Rate of Rats and Small Mammals

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Metabolic Rate of Rats and Small Mammals

• Chris Klundt Herlina Moeljadi Julie Sauer
  Kevin Wright

• Client
• Dale A. Schoeller, Ph.D.
• Nutritional Sciences

Advisor Mitchell E. Tyler Associate Researcher
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Outline of Presentation

• Problem Statement
• Background Information
• Design Alternatives
• Final Design
• Future Work

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Problem Statement

• Redesign a flow system
• Measures flow rate, pp O2 and pp CO2
• Compatible with the current cage and equipment
• No significant pressure drops or leaks.
• Control water and urine.

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Background Information

• Calorimetry
• Measure O2 and CO2 levels
• Determine Metabolic Rate
• Heat production
• Fat
• Carbohydrates
• Protein-from urine
• Established, well researched system

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Background Information

• System in lab

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Design Alternatives

• Push
• Pump air into cages
• Pull
• Pull air through cages

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Push System
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Push System

• Pro
• One pump
• Detect all leaks
• More accurate air delivery to each cage
• Con
• If leak information is lost
• Less sensitive to leaks around cage

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Pull System - 1
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Pull System - 1

• Pro
• More popular system
• Extra air if leak, no information lost
• Extreme precision air flow
• Con
• Cannot detect all leaks
• Expensive

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Final Design-Pull
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Final Design

• Pro
• More popular system
• Extra air if leak, no information lost
• Cost effective
• Con
• Cannot detect all leaks

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Design Matrix
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Final Design

• Solenoid valves by Humphrey
• 100 each
• 10 valves
• 1000
• Compression fitted valves by Hoke
• 40 each
• 5 valves
• 200

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Future Work

• Construct system
• Testing for leaks and accuracy
• Solve practical problems