1' Define conformation

1
McCurdy - Group exercises (Background)
1. Define conformation 2. Draw two
conformations of this compound HO-(CH2)3-OH 3.
Is one more stable than the other? Why or why
not? 4. What structural changes to this
compound would cause it to have fewer
conformations?
2
(No Transcript)
3
(No Transcript)
4
McCurdy - Group exercises (Background)
5. Arrange the following in order of size
(smallest to largest)
Ibuprofen, bacterium, water molecule, enzyme,
virus
6. Where does receptor fit in this list?
Antibody?
5
(No Transcript)
6
(No Transcript)
7
(No Transcript)
8
McCurdy - Group exercises (Background)
7. Arrange the following drugs in order of size
(smallest to largest)
Herceptin, lipitor, fluoxetine, erythromycin,
enbrel
http//www.3dchem.com/
9
(No Transcript)
10
Fluoxetine Prozac
11
Lipitor
http//www.3dchem.com/moremolecules.asp?ID19othe
rnameLipitor
(C33H34FN2O5)2 Ca 3H2O
12
Erythromycin antibiotic
http//www.3dchem.com/molecules.asp?ID18
C37 H67 N 013
13
Insulin peptide hormone
http//www.3dchem.com/molecules.asp?ID196
C254H377N65O75S6
14
Enbrel fusion of two proteins (recombinant DNA
product). Arthritis
http//en.wikipedia.org/wiki/Etanercept
C2224H3475N621O698S36
15
Herceptin monoclonal antibody
http//www.3dchem.com/molecules.asp?ID194
C6470H10012N1726O2013S42