Pedigree Exercise Review

1
Pedigree Exercise Review

• Section 12-2

2
Question 1

• 1. Suds Disease (SD) is an autosomal recessive
  disease resulting from a spongy metabolism. Use
  (S) for the non-Suds allele and (s) for the
  Suds allele. Fill in the genotypes of the people
  represented in the pedigree below

Notes SD autosomal recessive disease. Use S
and s
normal m normal f
diseased m diseased f
3

Ss
Ss
Ss
4
Question 2

• 2. Squidwards Disease (SqD) is a rare autosomal
  dominant disease that appears around the age of
  50. It involves the breakdown of nose cells,
  causing drooping, and eventually death. Use (Q)
  for Squidwards Disease allele and (q) for the
  non-Squidwards Disease allele. Determine the
  possible genotypes of the pedigree below.

5

qq
Qq
qq
Qq
Qq
6
Question 3

• 3. Analyze the following pedigree and determine
  the genotypes of the individuals. If the second
  gene can not be determined, place a dash (-) next
  to the dominant gene. Begin with the recessive
  individuals. This pedigree analyzes
  tongue-rolling, which is an autosomal dominant
  characteristic in Bikini Bottom. Use (R) for
  roller and (r) for non-roller to write the
  alleles.

7
R-
8
Self Test!
Normal male
Normal female
XdXD
XDX-
XDX-
XDX-
XdXD
XdXD
XDX-
XDX-
XDXd
A x-linked recessive disease. Use D and d for the
alleles. Fill in the genotypes. Data for many
generations reveal that there are no diseased
females.
Notice Females are carriers. There are no cases
of direct male to male transmission because males
transmit their X chromosomes to their daughters
and not to their sons.
9
Next Class

• Surprise Quiz!