Figure 19-50Molecular formula of the phosphatidylinositides. - PowerPoint PPT Presentation

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Figure 19-50Molecular formula of the phosphatidylinositides.

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Figure 19-52 A phospholipase is named according ... What's weird about this guy? ... Figure 20-15 Regulation of glucose uptake in muscle and fat cells. Page 735 ... – PowerPoint PPT presentation

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Title: Figure 19-50Molecular formula of the phosphatidylinositides.


1
Figure 19-50 Molecular formula of the
phosphatidylinositides.
Page 707
2
Figure 19-52 A phospholipase is named according
to the bond that it cleaves on a
glycerophospholipid.
Page 709
3
Figure 18-26a The livers response to stress.
Stimulation of a-adrenoreceptors by epinephrine
activates phospholipase C to hydrolyze PIP2 to
IP3 and DAG.
Page 652
4
Figure 19-51 Role of PIP2 in intracellular
signaling.
Page 708
5
Figure 19-23 Domain organization in a variety of
receptor tyrosine kinase (RTK) subfamilies.
Page 684
6
Figure 19-27a Growth pattern of vertebrate cells
in culture. (a) Normal cells stop growing
through contact inhibition once they have formed
a confluent monolayer.
(b) In contrast, transformed cells lack contact
inhibition they pile up to form a multilayer.
7
Figure 19-28 Variation of the cancer death rate
in humanswith age.
Page 688
8
Figure 19-29a Transformation of cultured chicken
fibroblasts by Rous sarcoma virus. (a) Normal
cells adhere to the surface of the culture
dish.(b) On infection with RVS, these cells
become rounded and cluster together in piles.
(a)
(b)
Page 689
Page 689
9
Figure 19-38 The Ras-activated MAP kinase cascade.
Page 696
10
Figure 19-40 MAP kinase cascades in mammalian
cells.
Page 698
11
Membrane Transport Chapter 20
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Figure 20-2 Permeability correlates with membrane
solubility.
Page 728
19
Figure 20-4 General kinetic scheme for membrane
transport.
Page 729
20
Figure 20-6 Ion transport modes of ionophores.
Page 730
21
Figure 20-7 Valinomycin.
A carrier ionophore.
Page 730
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22
Figure 20-8a Valinomycin X-ray structures. (a)
The K complex.
Page 731
23
Figure 20-8b Valinomycin X-ray structures.(b)
Uncomplexed valinomycin.
Page 731
24
Figure 20-10 Gramicidin A. This polypeptide
consists of 15 alternating D- and L-amino acid
residues and is blocked at both its N- and
C-termini.
A channel forming ionophore.
Page 732
Whats weird about this guy?
25
Figure 20-11a NMR structure of gramicidin A
embedded in a dimyristoyl phosphatidylcholine
bilayer. (a) View from within the bilayer along
the homodimeric helixs twofold axis. b) View
perpendicular to the bilayer plane (rotated 90
about the horizontal axis relative to Part a).
Page 732
26
Figure 20-12 The X-ray structure of a subunit of
E. coli maltoporin in complex with a maltodextrin
of 6 glucosyl units (Glc6).
Page 733
27
Figure 20-13 Predicted secondary structure and
membrane orientation of the glucose transporter.
Page 734
28
Figure 20-14 Alternating conformation model for
glucose transport.
Page 734
29
Figure 20-15 Regulation of glucose uptake in
muscle and fat cells.
Page 735
30
Figure 20-16a X-Ray structure of the KcsA K
channel.(a) Ribbon diagram. (b) A cutaway
diagram
Page 736
31
Figure 20-16c X-Ray structure of the KcsA K
channel.(c) A schematic diagram.
Page 736
32
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Figure 20-18 Uniport, symport, and antiport
translocation systems.
Page 739
38
Figure 20-19 Putative dimeric structure of the
(NaK)ATPase indicating its orientation in the
plasma membrane.
Page 739
39
Figure 20-20 Reaction of 3HNaBH4 with
phosphorylated (NaK)ATPase.
Page 740
40
Figure 20-21 Kinetic scheme for the active
transport of Na and K by (NaK)ATPase.
Page 741
41
Figure 20-22a Cardiac glycosides. (a) The leaves
of the purple foxglove plant are the source of
the heart muscle stimulant digitalis.
Page 742
42
Figure 20-22b Cardiac glycosides. (b) Digitoxin
(digitalin) and ouabain are among the most
commonly prescribed cardiac drugs.
Page 742
43
Figure 20-23 Kinetic mechanism of Ca2ATPase.
Page 742
44
Figure 20-24aX-Ray structure of the Ca2ATPase
from rabbit muscle sarcoplasmic reticulum. (a)
A tube-and-arrow diagram. (b) A schematic diagram
Page 743
45
Figure 20-25 Transport of glucose by the
PEP-dependent phosphotransferase system (PTS).
Page 745
46
Figure 19-64 Insulin signal transduction.
Page 719
47
Alfonse, Biochemistry makes my head hurt!!
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