Title: Figure 19-50Molecular formula of the phosphatidylinositides.
1Figure 19-50 Molecular formula of the
phosphatidylinositides.
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2Figure 19-52 A phospholipase is named according
to the bond that it cleaves on a
glycerophospholipid.
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3Figure 18-26a The livers response to stress.
Stimulation of a-adrenoreceptors by epinephrine
activates phospholipase C to hydrolyze PIP2 to
IP3 and DAG.
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4Figure 19-51 Role of PIP2 in intracellular
signaling.
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5Figure 19-23 Domain organization in a variety of
receptor tyrosine kinase (RTK) subfamilies.
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6Figure 19-27a Growth pattern of vertebrate cells
in culture. (a) Normal cells stop growing
through contact inhibition once they have formed
a confluent monolayer.
(b) In contrast, transformed cells lack contact
inhibition they pile up to form a multilayer.
7Figure 19-28 Variation of the cancer death rate
in humanswith age.
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8Figure 19-29a Transformation of cultured chicken
fibroblasts by Rous sarcoma virus. (a) Normal
cells adhere to the surface of the culture
dish.(b) On infection with RVS, these cells
become rounded and cluster together in piles.
(a)
(b)
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9Figure 19-38 The Ras-activated MAP kinase cascade.
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10Figure 19-40 MAP kinase cascades in mammalian
cells.
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11Membrane Transport Chapter 20
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18Figure 20-2 Permeability correlates with membrane
solubility.
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19Figure 20-4 General kinetic scheme for membrane
transport.
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20Figure 20-6 Ion transport modes of ionophores.
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21Figure 20-7 Valinomycin.
A carrier ionophore.
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Whats weird about this molecule?
22Figure 20-8a Valinomycin X-ray structures. (a)
The K complex.
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23Figure 20-8b Valinomycin X-ray structures.(b)
Uncomplexed valinomycin.
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24Figure 20-10 Gramicidin A. This polypeptide
consists of 15 alternating D- and L-amino acid
residues and is blocked at both its N- and
C-termini.
A channel forming ionophore.
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Whats weird about this guy?
25Figure 20-11a NMR structure of gramicidin A
embedded in a dimyristoyl phosphatidylcholine
bilayer. (a) View from within the bilayer along
the homodimeric helixs twofold axis. b) View
perpendicular to the bilayer plane (rotated 90
about the horizontal axis relative to Part a).
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26Figure 20-12 The X-ray structure of a subunit of
E. coli maltoporin in complex with a maltodextrin
of 6 glucosyl units (Glc6).
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27Figure 20-13 Predicted secondary structure and
membrane orientation of the glucose transporter.
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28Figure 20-14 Alternating conformation model for
glucose transport.
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29Figure 20-15 Regulation of glucose uptake in
muscle and fat cells.
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30Figure 20-16a X-Ray structure of the KcsA K
channel.(a) Ribbon diagram. (b) A cutaway
diagram
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31Figure 20-16c X-Ray structure of the KcsA K
channel.(c) A schematic diagram.
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37Figure 20-18 Uniport, symport, and antiport
translocation systems.
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38Figure 20-19 Putative dimeric structure of the
(NaK)ATPase indicating its orientation in the
plasma membrane.
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39Figure 20-20 Reaction of 3HNaBH4 with
phosphorylated (NaK)ATPase.
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40Figure 20-21 Kinetic scheme for the active
transport of Na and K by (NaK)ATPase.
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41Figure 20-22a Cardiac glycosides. (a) The leaves
of the purple foxglove plant are the source of
the heart muscle stimulant digitalis.
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42Figure 20-22b Cardiac glycosides. (b) Digitoxin
(digitalin) and ouabain are among the most
commonly prescribed cardiac drugs.
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43Figure 20-23 Kinetic mechanism of Ca2ATPase.
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44Figure 20-24aX-Ray structure of the Ca2ATPase
from rabbit muscle sarcoplasmic reticulum. (a)
A tube-and-arrow diagram. (b) A schematic diagram
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45Figure 20-25 Transport of glucose by the
PEP-dependent phosphotransferase system (PTS).
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46Figure 19-64 Insulin signal transduction.
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47Alfonse, Biochemistry makes my head hurt!!
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