Chemistry 4202 Biochemistry 1 Dr' E' Mintzer

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Chemistry 4202 Biochemistry 1Dr. E. Mintzer
1MBN.pdb Watson HC, Kendrew JC, 1973/4/5
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BiochemistryGoals and Objectives

• The structure/function relationships of
  biomolecules
• Amino acids/peptides/proteins
• Classes of proteins
• Structural
• Storage/transport
• Enzymes
• Carbohydrates
• Nucleic acids
• Lipids/membranes
• Metabolic Pathways
• Glycolysis
• Pentose Phosphate Pathway
• Citric Acid Cycle
• Regulation and Control of Metabolism
• Oxidative Phosphorylation

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Review of Chemical Principles

• Types of chemical bonding and interactions
• Covalent bonding
• H-bonding
• van der Waals interactions
• Hydrophobic interactions
• Organic Reactions and Stereochemistry
• Chemical Kinetics
• Chemical Equilibria
• Thermodynamics

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The (theorized) Origin of LifeMiller and Urey
(1953)
Nucleic acids (adenine ((HCN)5) can be formed
from a simple precursor (HCN), a compound found
in high concentrations on primordial earth.
Sugars were probably formed from formaldehyde
(CH2O) catalyzed by metals
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