Simply CIDRs'

1
Simply CIDRs.

• Amy McLean Wm. Graves
• University of Georgia

2
What is a CIDR?

• Intravaginal progesterone releasing device
• Nylon core with silicone rubber cover
• Easy application removal
• Delivers natural progesterone (1.38 ng)
• Slow release 7 day duration
• Prevents estrus expression induces cycles

3
Controlled Internal Drug Release
4
CIDR Advantages

• FDA Approved for dairy heifers
• Excellent retention rates
• Over the counter
• Possible Reuse
• Decrease Reproduction Costs

5
CIDR Support

• Treatment with intravaginal
• Progesterone (CIDR) for 7 days
• increased the proportion of heifers that were in
• estrus (59 vs. 21 w/o insert) and formed
• functional CL (55 vs. 12 w/o) after insert
• removal.
• Synchrony of estrus functional CL formation
• was even greater in heifers that received a
• CIDR insert and EB on day 7.
• S.K. Johnson et al., 1997, Fort Hays State
  University, Hays, KS.
• Abs. Jrnl. Ani. Sci. 751.

6
CIDR Support continued

• Conception rates are not reduced after estrus
  synchronization with CIDR and PG. A.M.
  Richardson et al., 2001. Kansas State Univ. Abs.
  Jrnl. Ani. Sci. 841
• CIDRs can be used for resynchronizing heifers
  that do not become pregnant after first breeding
  by inserting the CIDR 13 days after breeding and
  leaving in for 7. Bill Thatcher, Dairy Today,
  Apr. 2002.

7
CIDRs with other Treatments

• Estradiol benzoate (EB) administered after CIDR
  insert and PG on day 7 increased conception rates
  in heifers. C.L. Barnett et al., 1999. Abs.
  Am.Soc. Ani. Sci. Southern Sect.
• Administration of EB at CIDR insertion increases
  TAI pregnancy rates for Angus crossbred cows
  of Bos indicus influence.
• G.A. Bridges et al. 2002, University of Florida
  Abs. Am. Soc. Of Ani. Sci. Southern Section.

8
CIDRs and more Treatments

• Use of estradiol cypionate (ECP) at 1 mg with
  CIDR increased return rate to estrus without
  affecting conception at the previous TAI and
  increased the 23 day pregnancy rate. M.A.
  Medina-Britos et al., 2001. Abs. Jrnl. Ani. Sci.
  841.
• Estrus detection rates and pregnancy rates were
  lower in heifers treated with GnRH and CIDR
  insert. B.A. Hensley et al., 2001. Abs. Jrnl.
  Ani. Sci. 841.

9
Treatment 1 Heat Detect CIDR PGF

• Day 0 Insert CIDR
• Day 7 Remove CIDR
• Inject PGF
• Day 8-12 Heat Detect AI
• Heat Detection observed with HeatWatch System,
  an
• electronic mount or pressure sensing system used
  to
• aid in estrus detection.

10
Treatment 2 Heat Detect Control (CIDR only)

• Day 0 Insert CIDR
• Day 6 Inject PGF
• Day 7 Remove CIDR
• Day 8-12 Heat Detect AI
• Heat detection observed with Heatwatch.

11
The best way to have a good idea is to have
lots of ideas. -Linus Pauling
(1901-1994)