Bipolar Disorder Medications: Adverse Events

1
Bipolar Disorder MedicationsAdverse Events

• Second-generation antipsychotics
• Hyperglycemia and diabetes mellitus
• Neuroleptic malignant syndrome and tardive
  dyskinesia
• Increased risk of death in elderly patients with
  dementia
• Aripiprazole, olanzapine, and risperidone
  cerebrovascular adverse events in elderly
  patients with dementia
• Ziprasidone QTc prolongation, EKG changes
• Clozapine orthostatic hypotension
• Lamotrigine acute multiorgan failure
• Valproate urea cycle disorders, somnolence in
  the elderly, thrombocytopenia, intrauterine
  developmental delay
• Carbamazepine do not use with other
  carbamazepine products

Source Prescribing Information. In Physicians
Desk Reference. 59th ed. Montvale, NJ Medical
Economics Co 2005 Pellock JM. Epilepsia.
198728(suppl 3)S64-S70 Leppik I. Contemporary
Diagnosis and Management of the Patient With
Epilepsy. Newtown, PA Handbooks in Health Care
2001. Farah A. Prim Care Companion J Clin
Psychiatry. 20057268-274.