Lehninger Principles of Biochemistry 5/e

1
Protein Function
2
(No Transcript)
3
Protoporphyrin
4
Heme
5
Spacefill representation of heme
6
Iron in Mb-bound heme can not be oxidized
7
Myoglobin
8
Ligand binding to heme
9
Mb increases the selectivity of O2 binding
10
Ligand binding equilibrium
11
(No Transcript)
12
O2 binding by Mb
13
(No Transcript)
14
Hb subunits are homologous to Mb
15
(No Transcript)
16
Dominant interactions in Hb tetramer
17
T-Hb stabilizing interactions
18
T-Hb more stabilizing interactions
19
(No Transcript)
20
Going from T to R
21
Going from T to R
22
(No Transcript)
23
Going from T to R functional consequences
24
The Hill coefficient
25
Effect of pH on O2 binding
26
Effect of pH on O2 binding
27
The CO2 transport
28
Binding of CO2 stabilizes T-Hb
29
(No Transcript)
30
(No Transcript)
31
(No Transcript)
32
(No Transcript)
33
(No Transcript)
34
(No Transcript)