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Function Express

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Are co-expressed genes co-regulated? ... Sunita Koul. Rekha Meyer. Mukesh Sharma. Joanne Zhao. Software Project Manager. Srikanth Adiga ... – PowerPoint PPT presentation

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Title: Function Express


1
Function Express
November 30, 2007
2
Function Express Architecture
MGA
MAC
LocalDB (MySQL)
Chip Data Virtual Experiment Data
Integrated DB (Oracle 9i)
Individual
Chip Data Gene Annotations Analysis
LocalDB (MySQL)
Bioinformatics Core
Laboratory
3
Function Express Log in Auto Update
4
Function Express Experiment Menu
5
Creating and Opening Virtual Experiments
6
Function Express Overview
7
Importing Data and Security Features
8
  • Security Movie

9
Manipulating Categories
10
Function Express Viewers
11
Plotting Microarray Data
12
Function Express Viewers
Clinical Data
Category History
Probeset Data
Probeset Comments
Category Comments
13
BioCarta Pathway browser
14
Gene Inspector
15
Browsing Gene Annotations
16
Manipulating and Importing Analysis Results Movies
17
Function Express Analyzing Data
18
SAM PCA Weighted Voting
19
Function Express Analyzing Data
  • SVM
  • Consensus Clustering
  • Comparative Marker Selection

20
Function Express What to do after analysis?
  • Are co-expressed genes co-regulated?
  • What regulatory networks are operating/perturbed
    in your experimental paradigm?
  • What pathways/processes emerge from a set of
    interesting genes?
  • Promoter Analysis Pipeline
  • Gene Network Viewer
  • IPA

21
Promoter Analysis Pipeline
22
Gene Network Viewer
23
Acknowledgments
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