Biomanufacturing in North Carolina

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Biomanufacturingin North Carolina
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Biomanufacturing in N.C.

• What is biotechnology?
• A collection of technologies that use living
  cells and/or biological molecules to solve
  problems and make useful products.

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Biomanufacturing in N.C.

• The making of these products is called
  biomanufacturing or bioprocessing.

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Biomanufacturing in N.C.

• A Growing Industry in N.C.
• 16 biomanufacturing companies
• More than 30 other companies engaged in related
  manufacturing of pharmaceuticals, diagnostics and
  medical devices
• Together, they employ more than 20,000 people.

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Biomanufacturing in N.C.

• Types of products made in N.C. include
• Vaccines for humans and animals
• Biopharmaceuticals
• Amino acids
• Industrial enzymes
• Therapeutics isolated from blood
• Custom DNA sequences

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Biogen Idec
Produces biopharmaceuticals to treat cancer,
multiple sclerosis and inflammatory diseases.
Its large-scale manufacturing in Research
Triangle Park is one of the largest cell culture
facilities in the world.
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Ajinomoto
Is a world leader in the production of amino
acids, the building blocks of proteins. Like many
bioprocessing facilities, the Raleigh plant
operates at full capacity 24 hours a day, 365
days a year.
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Diosynth RTP
Is a world leader in production of recombinant
protein biopharmaceuticals. Its state-of-the-art
facilities are located in Research Triangle Park.
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AlphaVax

• Is developing a new vaccine technology with
  broad applications against infectious disease,
  cancer and biodefense threats. Its manufacturing
  plant is located in Lenoir.

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Novozymes North America
Is located on 1,600 acres in Franklinton. It is
the largest multi-purpose enzyme manufacturing
plant in the United States and employs
approximately 350 people.
Novozymes is the biotech-based world leader in
industrial enzymes and microorganisms.
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Embrex

• Is an international ag biotech company that
  developed the first in ovo (in the egg) injection
  system. It eliminates the need for manual
  vaccination of newly hatched broiler chicks. The
  manufacturing plant is located in
• Laurinburg.

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Wyeth Vaccines

• Operates one of the worlds largest vaccine
  facilities in Sanford. The vaccines that
  eliminated small pox and polio in the U.S. came
  from Wyeth laboratories.

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Greer Labs

• Is a leading supplier of allergy testing and
  treatment materials. Its manufacturing facility
  is located in
• Lenoir.

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KBI BioPharma

• Is a contract biomanufacturer in Durham. The
  company produces a variety of bio-pharmaceuticals
  for other companies.

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MWG Biotech

• Offers products and services for gene research.
• The company produces custom DNA sequences. The
  facility is located in High Point.

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Argos Therapeutics

• Is developing therapeutic vaccines in Durham,
  which are given to treat (instead of prevent)
  diseases such as cancer and HIV/AIDS.

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Biolex

• Produces hard-to-make therapeutic proteins by
  growing them in the aquatic plant Lemna
  (duckweed).
• The biomanufacturing plant is in Pittsboro.

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Talecris Biotherapeutics
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Archer Daniels Midland

• Is one of the largest agricultural processors
  in the world. The plant, in Southport, N.C.,
  produces citric acid.

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Corn Products International

• Produces high-fructose corn syrup and starch in
  Winston-Salem.

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Merck Co.

• Broke ground on a new biomanufacturing facility
  in 2004. When completed in 2008, the Durham
  facility will produce vaccines for chicken pox
  and measles-mumps-rubella (MMR).