Glucose Monitoring Within a Handspring Visor

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Glucose Monitoring Within a Handspring Visor

• Members Jeff Haar
• Josh Lemke
• Jeremy Saunier
• Adam Smith

Advisors Dr. John Estell Dr. David Kisor
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Diabetes in the United States

• Over 17 Million Americans have Diabetes
• Effects how the Body Regulates Blood Sugar Levels
• Currently No Cure
• Best Treated with Monitoring and Management

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Proposed Device

• Take Current Meters and combine with a PDA
• Utilize Intuitive User Interface
• Obtain the Glucose Reading Accurately

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Medical Issues

• Intended to Help Diabetics Manage Diabetes
• Must be Reliable
• Same Disclaimer as Common Meters
• Not Intended to Replace Test by Doctor
• Would Require FDA Approval

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Setbacks to our Design

• Abbott Laboratories
• Slow to Support
• Development Board
• Received with 3 Weeks Left in the Quarter
• Software Shipped Earlier

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Analog Hardware

• Designed to use Proprietary Strips
• Patent Information was used
• Need Further Support of Abbott Laboratories

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Examining Patents

• Patent Instructs
• Apply 600 mV
• Wait 5 60 Seconds
• Measure Current Through Circuit

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Building Prototype

• Modeled Strip as Variable Resistance
• Added a 875? Resistor to Measure Current
• Measured Voltage Drop of 0 14 mV

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Digital Hardware

• Function Requirements
• Components Used
• Components Description
• Block Diagram
• Verification

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Hardware Requirements

• Storage Memory
• Interface to Analog Hardware
• Interface to Visor
• Low Power Consumption
• Low Production Cost

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Component Functionality

• CPLD ? Interface
• Xilinx CoolRunner
• SRAM ? Temporary Storage
• 4 mb Toshiba SRAM
• Flash ROM ? Store Program
• 32 mb Toshiba CMOS FLASH MEMORY

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Component Functionality Cont

• 12 bit - A/D Converter
• Maximum Resolution of .5mV
• Needed 500 for Glucose levels 0 500
• Utilizes 1.15 V Reference
• Required Accuracy
• 0-14mV For Analog Signal
• To obtain Required Accuracy
• Gain of 20 ? (0 - 14 mV) x 20 (0 280)mv
• 280 .5 560 Discrete levels

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Block Diagram
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The CPLD Interface

• Communicate With Handspring
• Triggering System
• A/D Driver
• Used Xilinx Provided Program
• SRAM Driver
• Used Xilinx Provided Program
• Flash Rom Drive
• Untested

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Verification
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Software Development

• Functional Requirements
• Non-Functional Requirements
• GUI Functions
• Program Overview

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Functional Requirements

• Information Storage
• Glucose Reading
• Date/Time
• Comments
• Type
• Information Retrieval
• Graphically Display Data
• Backup to PC

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Non-Functional Requirements

• Simple and Intuitive to Use
• Quick to Input Reading
• Palm Appearance

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GUI Interface

• Built our own GUI
• Buttons
• Drop Down Lists
• Graphs

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Program Flow
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Future Considerations

• Production Costs
• Hardware Improvements
• Software Improvements

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Estimated Production Cost
Total 15
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Future Software Improvements

• Web Interface
• Ecivon SQL database
• Over both hot sync feature and wireless web
  access
• PC Interface
• Conduit to upload to PC
• Help information within program
• Allow multiple users
• Manual Entries

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Future Hardware Improvements

• Purge design off development board
• Create printed circuit board for module
• Use CPLD to average and store readings /
  eliminate SRAM as temporary storage location

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Future Hardware Improvements

• Initialization
• Store software in modules Flash ROM
• Begin reading immediately when strip is inserted
• Improve Power consumption
• Test power consumption of module
• Adapt design to meet specs of partnering Drug
  Company
• Cant create our own strips

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Conclusion

• Currently have proof of concept device
• Software functional
• Accurate hardware depends on proprietary strips

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For Further Information

• http//www2.onu.edu/stu5583/senior

• Any Questions?

• References
• http//www.niddk.nih.gov/health/diabetes/pubs/dmst
  ats/dmstats.htm
• Bayer, U.S. Patent No. 5,120,420 (June 9, 1992)

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Software Decision Matrix
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Software Block Diagram
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Software Verification

• Sample Database Created
• 2404 Records Spanning 2 Years
• 109 Kilobytes in size
• Tested Leap Year
• Platform Testing
• Used POSE to Test Different Operating Systems
• Total Installed Program Size
• 117 Kilobytes

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Extended Economic Information