Alcohols, Thiols

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Alcohols, Thiols Chapter 11
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Outline 1. Acidity and basicity of Alcohols and
Thiols 2. Synthesis of alcohols 3. Reactions of
alcohols 4. Glycols 5. Oxidation of thiols
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1. Acidity and basicity of Alcohols and
Thiols 2. Synthesis of alcohols 3. Reactions of
alcohols 4. Glycols 5. Oxidation of thiols
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In a polar solution, acidity of alcohols is
lower, than acidity of water due to the less
efficient solvation of the alkoxides (steric
reason).
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1.
Acidity and basicity of Alcohols and Thiols 2.
Synthesis of alcohols 3. Reactions of alcohols 4.
Glycols 5. Oxidation of thiols
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1.
Acidity and basicity of Alcohols and Thiols 2.
Synthesis of alcohols 3. Reactions of alcohols 4.
Glycols 5. Oxidation of thiols
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Zaitsevs rule During elimination hydrogen is
eliminated from the least hydrogenated carbon
The Zaitsevs rule controls regioselectivity of
elimination and based on different stability of
transition states with partial double bonds
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1.
Acidity and basicity of Alcohols and Thiols 2.
Synthesis of alcohols 3. Reactions of alcohols 4.
Glycols 5. Oxidation of thiols
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4. Glycols
5. Oxidation of thiols