L-???,????? - PowerPoint PPT Presentation

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L-???,?????

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L-??????. L-???????????????:???????,???????????????? ??????????4-6?/?????, ... ???????????,Drexler?(1994?)?18???????????????L-???(10mg/kg?min,20min)?????? ??(10 ... – PowerPoint PPT presentation

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Title: L-???,?????


1
L-???,????? ??????
Rhobert W.Evans,????
?????
2
??
  • L-?????
  • ????(NO)
  • ???
  • ???????
  • ???
  • ??????
  • ???/??
  • ?????
  • ????

3
L-?????
4
L-??????
  • ? L-??????????????????????,????????????????
  • ???????????4-6?/?????,??40-50????????

5
  • ?????????????????,??????????????????
  • ?????????????(??,80)???L-???????????????

6
  • ?????(NO)?????????(nitric oxide synthase,
    NOS)??,??????????????

7
??????
  • ??????
  • ?????(???,???Ca2)
  • ????(???,???Ca2 )
  • ?????(???,???Ca2 )???NO??????

8
???????(????cGMP)
  • ???????
  • ????????????
  • ????????
  • ??????????????(?????????)?

9
  • ?????????????????L-????????
  • ??????????????,NOS?L-????Km??2
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