BASE CATALYZED DEPROTONATION TO FORM AN ENOLATE - PowerPoint PPT Presentation

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BASE CATALYZED DEPROTONATION TO FORM AN ENOLATE

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BASE CATALYZED DEPROTONATION TO FORM AN ENOLATE. Base removes a-hydrogen ... a-Carbanion in resonance with Enolate anion. Nucleophilic site ... – PowerPoint PPT presentation

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Title: BASE CATALYZED DEPROTONATION TO FORM AN ENOLATE


1
BASE CATALYZED DEPROTONATION TO FORM AN ENOLATE
Base removes a-hydrogen
An Organic Base A Species that is capable of
donating a pair of electrons to a hydrogen.
2
BASE CATALYZED DEPRTONATION TO FORM AN ENOLATE
a-Carbanion is formed. Stabilization of carbanion
via resonance interaction with carbonyl group
3
BASE CATALYZED DEPRTONATION TO FORM AN ENOLATE
Enolate anion
a-Carbanion
4
BASE-CATALYZED DEPRTONATION TO FORM AN ENOLATE
Nucleophilic site
a-Carbanion in resonance with Enolate anion.
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