ageLOC

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The Best Science
Delivers the Best Results
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Best Science, Delivers the Best Results
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ageLOC Elements

• Gentle Cleanse Tone
• Radiant Day
• Transforming Night
• Foundational ageLOC regimen
• A powerful anti-aging system in its own right
• ADR friendly with 30-day supply packages

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Gentle Cleanse Tone

• Prepares the skin to receive advanced
  anti-aging ingredients and ageLOC
• Delivers the first infusion of ageLOC to the skin

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Unveil Youthful Radiance Each DayRadiant Day
SPF 22

• Infused with ageLOC and other advanced anti-aging
  ingredients proven to
• Increase radiance, reduce discoloration through
  melanin inhibition
• Increase cell turnover by 85
• Reduce fine lines, wrinkles pores
• Dramatically smooth and soften skin

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Indulge in Rich Renewal Each Night-Transforming
Night

• Infused with ageLOC and other advanced anti-aging
  ingredients proven to
• Works with skins natural nighttime repair and
  renewal processes, strengthening natural barriers
• Increase youthful cell turnover by 85
• Reduce look of fine lines, wrinkles pores
• Dramatically smooth and soften skin

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A Truly Transformational Experience

• Gentle Cleanse Tone
• Radiant Day
• Transforming Night
• Future Serum

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The most advanced product in Nu Skin
historyFuture Serum

• Maximum concentration of ageLOC
• ageLOC other Anti-aging ingredients proven to
  improve skin in 8 ways

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The Proof
Consumer Perception

• 12-week clinical study
• Consumer Perception Blinded Clinical Graders
• 8 different signs of aging
• The best results weve ever seen at Nu Skin

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8 Ways Youthful Skin Structure

• The foundation of young skin
• Ingredients proven to stimulate collagen by 150
  and reduce MMP activity by over 60 to conserve
  collagen

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IMPROVEMENT
In vitro studies
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8 Ways Skin Smoothness

• Smooth and refined skin texture you can feel
• Stimulate youthful cell renewal by 85 in only 5
  days, and 150 over time

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IMPROVEMENT
In vitro studies
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8 Ways Even Skin Tone
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• Tri-Phasic technology reduces unwanted melanin
  production
• Youthful cell renewal
• For best skin tone benefits, use with Radiant
  Day, SPF 22

IMPROVEMENT
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8 Ways Fine Lines Wrinkles
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• Driven by increased cell turnover youthful skin
  structure
• Still very gentle on the skin

IMPROVEMENT
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8 Ways Radiance
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• The highest response of all 8 signs
• Combined effect of improvements in all other
  signs leads to radiant skin

IMPROVEMENT
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8 Ways Pore Size
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• One of the most difficult signs of aging to
  affect
• Excellent for men who have larger pores
• Smaller pores increases radiance and luminosity

IMPROVEMENT
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8 Ways Skin Discoloration
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• Tri-phasic technology reduces activation,
  synthesis and expression of melanin
• Discoloration impacts perceived age more than any
  other quality

IMPROVEMENT
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8 Ways Hydration
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• Stimulates 85 increase in production of
  hyaluronic acid, skins own natural moisturizing
  factor
• Chronic dryness came up constantly in our
  research on aging

IMPROVEMENT
In vitro studies
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Consumer Perception

• All 8 signs of aging were reduced by more than
  50
• So in this study, participants perceived that

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Best Results
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• of participants showed improvement in two or more
  signs of aging in only 7 days

of participants showed improvement in overall
appearance, including fine lines, skin smoothness
and radiance at 12 weeks
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17 DAYS
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The Nu Skin Anti-Aging Portfolio
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First We IDENTIFY Youth Gene Clusters Groups
of genes that work together to influence how we
age. Second ageLOC includes proprietary
technologies and PARTNERSHIPS to measure aging at
the genetic level Third We reset Youth Gene
Clusters to a youthful BALANCE
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The ageLOC Difference

• ageLOC science RESETS YGCs to a more youthful
  pattern of activity
• boosting all genes is not the right approach
• Some genes become more active, some genes less to
  create the optimal youthful pattern
• Balance, harmony synergy

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Book of life human genome

• 2003 DISCOVERY AFTER 20 YEARS OF RESEARCH 25,000
  GENES FORM THE HUMAN GENOME
• TWENTY LABS (United States, the United Kingdom,
  France, Germany, Japan and China), HUNDREDS OF
  SCIENTISTS
• 3 BILLION

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NU SKINS UNIQUE ROSETTA STONE OF AGING GENETICS
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Exclusive Partnership
Dr. Tom Prolla Professor of Genetics University
of Wisconsin
Dr. Richard Weindruch Professor of
Medicine University of Wisconsin
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Landmark Science Publications
Lee et al, Science 1999 281390
Colman et al, Science 2009325201
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The Stanford Collaboration
Stanford University Two Dermatology
Professors Howard Chang, MD, PHD Anne Chang,
MD Professor of Genetics Stuart Kim, PhD
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Key insight from Stanford research
aging is an active genetic program that must be
continually reinforced to prevent a default state
of being young, at least in skin.
Howard Chang, MD, PhD Stanford University
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Sources of aging
Youth Gene Clusters (arSupermarkers)
Human Genome
LifeGen Caloric Restriction
Stanford U. Skin research
Genomics
Resetting Youth Gene Clusters (YGCs) Functionalit
y
AgeLOC antiaging products
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25,000 Genes from the Human Genome
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25,000 Genes from the Human Genome
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Youth
Youth
Youth
Youth
Youth
Youth
Youth
Youth
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YGC - Youth Gene Clusters
Up-regulation
Down-regulation
Youth Gene
Youth Gene
Youth Gene
Youth Gene
Youth Gene
Youth Gene
Youth Gene
Youth Gene
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Its about BALANCE
DOWN
UP
ageLOC RESET
YGCs
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Resetting Youth Gene Clusters to a More Youthful
Gene Profile
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Resetting Youth Gene Clusters with ageLOC
products
RESET SKIN
CONTROL SKIN
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Four YGCs Identified
Youth Gene Clusters
Skin Structure
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Four YGCs Identified
Signs of Aging
Youth Gene Clusters
Skin Structure
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Four YGCs Identified
Signs of Aging
Youth Gene Clusters
Fine Lines Wrinkles
Skin Structure
Youthful Skin Structure
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ageLOC science resetting is the key
Signs of Aging
Youth Gene Clusters
Fine Lines Wrinkles
Skin Structure
Discoloration
Youthful Skin Structure
Pigment
Skin Tone
Diagram Legend
Color Range
No Change
Up regulation
Down regulation
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ageLOC science resetting is the key
Youth Gene Clusters
Discoloration
Pigment
Skin Tone
Hydration
Hydration
Diagram Legend
Color Range
No Change
Up regulation
Down regulation
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ageLOC resetting is the key
Youth Gene Clusters
Hydration
Hydration
Diagram Legend
Color Range
No Change
Up regulation
Down regulation
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ageLOC science resetting is the key
Youth Gene Clusters
Texture, Smoothness
Cell Turnover
Radiance
Diagram Legend
CONTROL
RESET
Color Range
Pore Size
No Change
Up regulation
Down regulation
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EXCLUSIVITY OF AGELOC SCIENCE
resets gene controls. Back to the settings
observed during youth
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Just as perfect levels Perfect Sound
Pleasing Sound
Resetting Gene activity Youthful function
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Aging
Youthful
Youthful
Aging
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Competitors?
Aging
Aging
Game Over!
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The Future Pharmanex ageLOC?

• Exclusive research and product innovation based
  on the only proven method
• to extend life span

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THANK YOU