HighThroughput SNP Genotyping and Expression Screening Databases, Implimentation and Applications

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High-Throughput SNP Genotyping and Expression
Screening Databases, Implimentation and
Applications
T. Lu, J. Hampe, A. Wollstein, S. Wächter, R.
Vogler, C. Manaster, M. Will, S. Schreiber 1st
Department of Medicine, Christian-Albrechts
University, Kiel, Germany Humboldt-Universität
, Berlin, Germany
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Design Objectives

• The Mucosalab information management system
  provides the following features to our users
• Centralized repository for all laboratory data
• Easy to use interfaces for data management
• Integrated quality control and data integrity
  systems
• Scaleability and extendibility
• Make data analysis accessible to general users

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Platform Overview
The Internet
Mucosalab
Unix Workstations
Database server
Web server
Laboratory Computers
Outside Users
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High-Throughput SNP Genotyping
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Process Overview
Genotyping Results
Genedigger Results
SNP Typing Data Import Quality Control
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SNP Genotyping Database
IBD Genotyping Database Schema
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Quality Control ExampleMendel Checking
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Data accessibility ExampleGenedigger
http// www.mucosa.de/genedigger
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Process Overview
Genotyping Results
Genedigger Results
SNP Typing Data Import Quality Control
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Expression Screening Database
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Process Overview
35,000 Genes
Colitus Patient
mRNA
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Conclusion