Predictive value of CRP vs LDL-C (i)

1
Predictive value of CRP vs LDL-C (i)
Quintile of CRP (mg/L)
p value
gt4.19
gt2.09 to 4.19
gt1.08 to 2.09
gt0.49 to 1.08
lt 0.49
lt0.001
2.3
2.0
1.6
1.4
1.0
Adjusted RR of a first cardio-vascular event
relative risk adjusted for age, smoking status,
the presence or absence of diabetes mellitus,
blood pressure, use or nonuse of hormone
replacement therapy, and treatment assignment

• Ridker PM, et al. N Engl J Med 20023471557-1565.
  

2
Predictive value of CRP vs LDL-C (ii)
relative risk adjusted for age, smoking status,
the presence or absence of diabetes mellitus,
blood pressure, use or nonuse of hormone
replacement therapy, and treatment assignment
Ridker PM, et al. N Engl J Med 20023471557-1565.

3
High CRP/low LDL-C predicts high risk
High CRPHigh LDL
High CRPLow LDL
Low CRPHigh LDL
Low CRPLow LDL
3.9
2.6
1.3
Age-adjusted event rates per 1000 person-years
2.0
Low and high refer to levels below and above
the median values of CRP (1.52 mg/L) and LDL-C
(123.7 mg/dL)

• Ridker PM, et al. N Engl J Med 20023471557-1565.