GuillainBarr Syndrome Gheeyan Bahray

1
Guillain-Barré Syndrome(Ghee-yan Bah-ray)

• Presentation and Information Prepared by
• Carrie Phillips, Shaneen Fernandez, and Donna
  Horton

2
Quick Overview

• Guillain-Barré is a non-contagious autoimmune
  disorder that affects approximately 1 in every
  100,000 individuals in the United States.
• It is not clear yet if a specific disease-causing
  agent is involved so Guillain-Barré is called a
  syndrome rather than a disease

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Pathogenesis

• Acute autoimmune disorder
• There is involvement of T lymphocytes and B
  lymphocytes
• Brain is unable to send messages
• Legs and arms are commonly affected

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Etiology

• There are varying degrees of severity
• Onset usually occurs 1-3 weeks after exposure to
  a viral infection
• Destruction most often occurs in segments between
  the Nodes of Ranvier

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Clinical Manifestations

• Signs and Symptoms Include
• Paresthesia
• Muscle Weakness
• Possible Paralysis

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Treatment

• There is no cure for Guillain-Barré Syndrome, but
  there are treatments available
• Plasmapharesis
• Immunoglobulins

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Sources

• (1) Guillain-Barre Syndrome. Davids, Dr.
  Heather. University of Colorado School of
  Medicine. 2006. Viewed at http//www.emedicine.c
  om/pmr/topic48.htm
• "Guillain-Barré Syndrome Fact Sheet." NINDS. NIH
  Publication No. 05-2902. Viewed at
  http//www.ninds.nih.gov/disorders/gbs/detail_gbs.
  htm
• Van Doorn, P. A., (March 2003). Gullain-Barré
  syndrome. Retrieved September 2, 2008 from
  http//www.orpha.net/data/patho/GB/uk-Guillain.pdf
  
• Thomas. C. L. (18). (1997). Tabers Encyclopedic
  Medical Dictionary. Philadelphia F.A. Davis
  Company.
• Http//www.healthscout.com/ency/68/653/main.html
• http//www.ninds.nih.gov/disorders/gbs/gbs.htm
• http//www.neurologychannel.com/guillain/treatment
  .shtml
• http//www.emedicine.com/pkm/topic48.htmsectiont
  reatment