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Uniformed Services University of the Health Sciences ' ... Differential Diagnosis: The 'LIFE Lines' Lymphangitic spread of malignancy ... – PowerPoint PPT presentation

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Title: Chest Film Primer Images and Material courtesy of:


1
Chest Film Primer Images and Material courtesy
of
  • David S. Feigin, M.D.
  • Colonel (Ret), USA, MC
  • Professor of Radiology,
  • Uniformed Services University of the Health
    Sciences
  • A Systematic Approach To Abnormal Chest
    ImagesRadiographs And Computed Tomograms
  • Updates and compilation
  • Les Folio, DO, MPH
  • Col, USAF, MC, SFS
  • Associate Professor of Radiology,
  • Uniformed Services University of the Health
    Sciences

2
Main Menu
EXIT
  • 5 PATTERNS OF PATHOLOGY
  • Mass
  • Consolidative
  • Interstitial
  • Linear
  • Nodular
  • Vascular
  • Airway
  • Wall-Thickened
  • Obstructive
  • NORMAL ANATOMY
  • A-P Chest Radiograph
  • Lateral Chest Radiograph
  • THE SEARCH PATTERN
  • A-P Chest Radiograph
  • Lateral Chest Radiograph

3
Normal Anatomy- AP
? BACK MAIN MENU FORWARD ?
1. Gross Specimen
2. The Respiratory System A. The Airway
B. The Lungs and Diaphragm
  • Cardiovascular System
  • A. The Cavals

B. The Heart
SVC Edge
Left paratracheal stripe
LUL
C. The Pulmonary Arteries
RUL, next to minor fissure
D. The Pulmonary Veins
E. Aorta
3. The Bones, Bowel Gas, Azygous, etc.
Right Atrium
Left Ventricle
RML, next to right heart border
RLL
LLL
4
Normal Anatomy- Lateral
? BACK MAIN MENU FORWARD ?
1. Respiratory System A. The Airway
B. The Lungs and Diaphragm
RUL
Trachea
2. Cardiovascular System
Aorta
A. The Vessels
Right Pulmonary Artery
B. The Heart
Left Pulmonary Artery
Left main bronchus
RML, with minor fissure
3. The Bones (no link yet)
Right Ventricle
RLL, with major fissure
Left Ventricle
Inferior Vena Cava
5
Quiz yourself Mediastinum Lines, Edges
Recommendation Test yourself before advancing
to the answers
3
1
  • SVC Edge
  • Rt Paratracheal Line
  • Lt Paratracheal Stripe
  • (both red and black lines)
  • Aortic Arch
  • Descending Aorta
  • (only left edge seen, and not always)
  • Rt Atrium
  • Azygoesophageal edge
  • Lt Ventricle
  • Main Pulmonary Artery
  • AKA trunk, middle mogul

2
4
9
5
6
7
8
Mediastinum
Mid
6
Trachea
Lt MSB on end
Right Pulmonary Artery (red)
Left Pulmonary Artery (green)
Left Ventricle (curved line)
IVC (arrows)
Lateral
7
Main Menu
EXIT
  • The 5 PATTERNS OF PATHOLOGY
  • Mass
  • Consolidative
  • Interstitial
  • Linear
  • Nodular
  • Vascular
  • Airway
  • Wall-Thickened
  • Obstructive
  • NORMAL ANATOMY
  • A-P Chest Radiograph
  • Lateral Chest Radiograph
  • THE SEARCH PATTERN
  • A-P Chest Radiograph
  • Lateral Chest Radiograph

8
Search Pattern- AP
? BACK MAIN MENU FORWARD ?
  • PRELIMINARIES
  • Verify patient info, date, L and R
    markers
  • Note technique deficiencies
  • Quick look at both films for obvious
    abnormalities
  • FRONTAL
  • 1. LUNGS
  • Up and down
  • Side to side
  • Volume and Symmetry
  • 2. PERIPHERY
  • Pneumothorax (air)
  • Effusions (fluid)
  • 3. MEDIASTINUM
  • Contours
  • Edges
  • Shape
  • 4. TRACHEA AND MAIN BRONCHI
  • 5. HILA

9
Search Pattern- Lateral
? BACK MAIN MENU FORWARD ?
  • PRELIMINARIES
  • Verify patient info, date, L and R
    markers
  • Note technique deficiencies
  • Quick look at both films for obvious
    abnormalities
  • LATERAL
  • 1. SIZE AND SHAPE OF LUNGS AND DIAPHRAGMS
  • 2. AIRWAY
  • Neck to Hilum
  • Pulmonary Arteries
  • 3. Back of heart and darkening downward
  • 4. Up anterior mediastinum for darkening
  • 5. Down spine for vertebral bodies and darkening
  • 6. PERIPHERY
  • Abdomen
  • Anterior chest wall
  • Posterior ribs
  • Costophrenic angles

10
Main Menu
EXIT
  • 5 PATTERNS OF PATHOLOGY
  • Mass
  • Consolidative
  • Interstitial
  • Linear
  • Nodular
  • Vascular
  • Airway
  • Wall-Thickened
  • Obstructive
  • NORMAL ANATOMY
  • A-P Chest Radiograph
  • Lateral Chest Radiograph
  • THE SEARCH PATTERN
  • A-P Chest Radiograph
  • Lateral Chest Radiograph

11
1. Mass
? BACK MAIN MENU FORWARD ?
  • Mechanism - Local destruction of lung
    parenchyma
  • Radiological sign - Any localized opacity not
    completely bordered by fissures or pleura

12
1. Mass
? BACK MAIN MENU FORWARD ?
  • Differential Diagnosis
  • Malignancy - Primary or secondary
  • Granulomatous disease - Infectious or
    noninfectious, active or inactive
  • Other inflammation, including pneumonia and
    abscess, Benign neoplasm, Congenital abnormality
  • Crucial appearance characteristics for inactivity
  • Calcification central, lamellar
  • Evolution 2-year stability or regression

13
2. Consolidative (Alveolar) Pattern
? BACK MAIN MENU FORWARD ?
  • Mechanism
  • Produced in pure form and by ALVEOLAR FILLING
  • May be mimicked by alveolar collapse, as in
    airway obstruction
  • Rarely, confluent interstitial thickening
  • Radiological signs
  • Fluffy, cloud-like, coalescent opacities
  • Sharp edges when limited by fissures or pleura
  • Complete air bronchograms through the clouds

14
? BACK MAIN MENU FORWARD ?
Fluffy and cloud-like appearance Air bronchograms
THROUGH clouds
15
? BACK MAIN MENU FORWARD ?
Air bronchogram
Normal lung
Consolidated lung, with air in bronchioles
16
2. Consolidative (alveolar) Pattern
? BACK MAIN MENU FORWARD ?
  • Differential Diagnosis (5 general)
  • Hemorrhage - BLOOD - embolism, trauma
  • Exudate - PUS - pneumonia, pneumonitis
  • Transudate - WATER - congestion, ARDS
  • Secretions - PROTEIN - Mucous plugging, Alveolar
    proteinosis
  • Malignancy - CELLS - Alveolar cell carcinoma,
    Lymphoma

17
3. Interstitial Pattern
? BACK MAIN MENU FORWARD ?
  • Composition of pulmonary interstitium
  • Alveolar walls, septi
  • Connective tissue surrounding bronchi and
    vessels (peribronchial and perivascular
    spaces)
  • Mechanism
  • Thickening of lung interstices
  • Architectural destruction of interstitium
    (honeycomb or end stage lung)

18
3. Interstitial Pattern
? BACK MAIN MENU FORWARD ?
  • Radiological Signs
  • Linear form - reticulations (lines in all
    directions), septal lines (Kerley lines)
  • Nodular form - small, sharp, numerous, evenly
    distributed, uniform (especially uniform in
    shape) nodules
  • Destructive form - peripheral, irregular cyst
    formation

19
3. Interstitial Pattern
? BACK MAIN MENU FORWARD ?
  • Radiological Signs
  • Linear form - reticulations (lines in all
    directions), septal lines (Kerley lines)
  • Nodular form - small, sharp, numerous, evenly
    distributed, uniform (especially uniform in
    shape) nodules
  • Destructive form - peripheral, irregular cyst
    formation

20
? BACK MAIN MENU FORWARD ?
Reticular form (Lines in all directions)
Kerley B lines (horizontal septal)
21
3. Interstitial Pattern Linear Form
? BACK MAIN MENU FORWARD ?
  • Differential Diagnosis The LIFE Lines
  • Lymphangitic spread of malignancy
  • Inflammation
  • Fibrosis
  • Edema

22
3. Interstitial Pattern
? BACK MAIN MENU FORWARD ?
  • Radiological Signs
  • Linear form - reticulations (lines in all
    directions), septal lines (Kerley lines)
  • Nodular form - small, sharp, numerous, evenly
    distributed, uniform (especially uniform in
    shape) nodules
  • Destructive form - peripheral, irregular cyst
    formation

23
? BACK MAIN MENU FORWARD ?
Multiple small nodules, uniform in shape and
distribution
24
3. Interstitial Pattern- Nodular Form
? BACK MAIN MENU FORWARD ?
Granulomatous Diseases Infectious Tuberculosis
Atypical mycobacterial diseases - especially
MAI Fungal diseases, especially Histoplasmosis
Coccidioidomycosis Blastomycosis (N. A. and
S. A.) Cryptococcosis Sporotrichosis Bacteria
l diseases, especially Nocardiosis Actinomyco
sis Non-infectious Sarcoidosis Hypersensitivity
Pneumonitis (HP) Vasculitis-granulomatosis
diseases Wegeners Lymphocytic Bronchocentri
c Allergic (Churg-Strauss) Langerhans
Granulomatosis (eosinophilic granuloma,
histiocytosis) (LCG)
  • Differential Diagnosis

Pneumoconiousus Granulomatous Silicosis Beryllio
sis Benign Coal Workers Pneumoconiosis Sidero
sis Stannosis
1. Granulomas
2. Hematogenous Spread of Malignancy
3. Pneumoconiosus
25
3. Interstitial Pattern
? BACK MAIN MENU FORWARD ?
  • Radiological Signs
  • Linear form - reticulations (lines in all
    directions), septal lines (Kerley lines)
  • Nodular form - small, sharp, numerous, evenly
    distributed, uniform (especially uniform in
    shape) nodules
  • Destructive form - peripheral, irregular cyst
    formation

26
? BACK MAIN MENU FORWARD ?
Early findings are non-specific. The peripheral
cyst formation (End-Stage Lung) is a late
finding.
Peripheral cyst formation, Honeycomb lung
27
4. Vascular Patterns
? BACK MAIN MENU FORWARD ?
  • Mechanism - increased, or decreasedperfusion,
    altering diameter of pulmonaryvessels
  • Radiological signs - changes in diameterof
    specific vessels

28
4. Vascular Patterns
? BACK MAIN MENU FORWARD ?
  • Common examples
  • Congestion - engorged veins, especially upper
    lungs
  • Emphysema - diminished vessels
  • Shunt vascularity - all vessels enlarged
  • Lymphangitic carcinoma - irregular infiltration
    around vessels may resemble vessel enlargement
  • Arterial hypertension - large central arteries
    with peripheral tapering
  • Thromboembolism - locally diminished vessels with
    possible vessel mass centrally located
  • Bronchial circulation - irregular vessels in
    unusual directions

29
? BACK MAIN MENU FORWARD ?
Engorged vessels, especially upper lungs
Congested vasculature
30
? BACK MAIN MENU FORWARD ?
Diminished vasculature
Emphysematous changes
31
? BACK MAIN MENU FORWARD ?
Enlarged pulmonary trunk (middle mogul)
Prominent left pulmonary artery
32
5. Airway (Bronchial) Patterns
? BACK MAIN MENU FORWARD ?
  • Mechanism
  • Complete or partial obstruction of airways
  • Thickening of airway walls
  • Forms
  • Complete airway obstruction - opacity and
    decreased volume
  • Partial obstruction - lucency and increased
    volume
  • Wall thickening - tram tracks, central cystic
    spaces or circles

33
? BACK MAIN MENU FORWARD ?
Flattened diaphragms on lateral
Bronchial wall thickening (circles and tram
tracks)
34
5. Airway (Bronchial) Patterns
? BACK MAIN MENU FORWARD ?
  • Differential diagnosis
  • Opacities - endobronchial malignancies,
    granulomas, inflammatory, benign or congenital
    masses, mucous plugs, foreign bodies
  • Lucencies - COPD, cysts, blebs, pneumatoceles
  • Thickening - bronchiectasis, chronic bronchitis

35
5. Airway (Bronchial) Patterns
? BACK MAIN MENU FORWARD?
  • Lobar atelectasis (collapse)
  • Primary Signs
  • Vessel number assymetry
  • Fissure as edge
  • Secondary signs
  • Volume loss
  • Elevation of diaphragm
  • Shift of mediastinum and ribs

36
Atelectasis Patterns
Right
Left
Upper
RUL
LUL
Lower
LLL
RLL
37
? BACK MAIN MENU EXIT ?
Vessel Asymmetry
Left lower lung collapse
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