Fig' 1 LTD in the cerebellar cortex'

1
Fig. 1 LTD in the cerebellar cortex. A.
neuronal circuit in the cerebellar cortex
(modified from Cajal, 1911). Yellow needles,
stimulating electrodes. Blue needle, recording
microelectrode. Arrows indicate directions of
signal propagation. B, LTD observed in a
cerebellar slice. The oblique shade indicates
conjunctive stimulation at 1 Hz for 5 min.

2
Parallel fiber
Purkinje cell
Fig. 2 Signal transduction pathway for LTD
induction (7).
Climbing fiber
3

LTD
PC
PF
CC
GR
Climbing fiber
Mossy fiber
Error signal
IO
Cerebellar/vestibular nucleus
Fig. 3 Cerebellar microcomplex as a unit machine
capable of error learning. CC, cerebellar cortex.
PC, Purkinje cell. PF, parallel fiber. GR,
granule cell. IO, Inferior olive.
4
Premotor cortex
Forward model
Motor cortex
Internal feedback
Motor apparatus
Corticospinal tract
External feedback
Fig. 4 Cerebrocerebellar comunication loop that
may provide a feedforward model for the voluntary
motor system. CF, climbing fiber. MF, mossy
fiber. BF, beaded fiber.