Title: Grants for Health Services Research from the Agency for Healthcare Research and Quality AHRQ
1Grants for Health Services Research from the
Agency for Healthcare Research and Quality (AHRQ)
Ryan Mutter, Ph.D. Agency for Healthcare
Research and Quality April 19, 2006 UMBC Office
of Sponsored Programs
2AHRQ
- Approximately 80 percent of AHRQ's budget is
invested in grants and contracts focused on
improving healthcare.
3Two Types of Research
- New Knowledge
- Translation and Implementation
4Mission
To improve the quality, safety, efficiency, and
effectiveness of healthcare for all Americans
5Mission
- AHRQ achieves its mission through programs
designed to - Improve clinical practice
- Improve the healthcare system's ability to
provide access to and deliver high quality,
high-value healthcare - Provide policymakers with the ability to assess
the impact of system changes on outcomes,
quality, access to, cost, and use of healthcare
services.
6Areas of Emphasis
- System capacity and bioterrorism
- Data development
- Care management
- Cost, organization, and socio-economics
- Health information technology
- Quality/safety of patient care
- Long-term care
- Pharmaceutical outcomes
- Training
- Prevention
7Growing Focus on Results
- Research promoting AHRQ goals
- Actionable research results
- Shorter research turnaround
- More demonstrations, planning, evaluation
projects (often done through contracts) - Leveraging funds for broad impact
- Priority populations policy
-
8Grant Example (1) Impact of Specialty Hospitals
on Procedure Utilization
- RO1, PI B. Nallamothu
- Background concern that specialty hospitals
siphon off most profitable procedures from
general hospitals and create supplier induced
demand for these procedures. - Policy implications relevant to debate in
Congress over whether to declare moratorium on
specialty hospital construction - Aim 1 Impact of opening of specialty hospitals
on volumes for 4 procedures (e.g., coronary
artery bypass total knee anthroplasty) at
competing general hospitals - Aim 2 Impact on population rates for 4
procedures - Design longitudinal analysis of population level
data by regions - Data Medicare 1994-2000
9Grant Example (2)Public Reporting (PR) and
P4PImpact on Safety Net Hospitals (SNHs)
- R03, PI Adams Dudley
- Background Much activity and interest but little
research on impact of PR and P4P on SNHs - Questions (1) What are SNH executives concerns
about PR and P4P and their suggestions for future
programs? (2) How feasible and acceptable are
their suggestions in view of regulators, payers,
and non SNH executives? - Method Documentary analysis of regulations and
practices in Californina, qualitative in-depth
interviews with 2 types of hospital executives
and other stakeholders. - Analysis iterative using qualitative software
10Funding Announcements
- Requests for Applications (RFAs)
- stimulate activity in AHRQ programmatic research
priority areas - single application receipt date is specified
- amount of funds earmarked for the initiative and
the number of awards likely to be funded
announced - Program Announcements (PAs)
- continuing, new, or expanded program interests
for which grant or cooperative agreement
applications are invited -
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14RFAHS-06-030
- Improving Patient Safety through Simulation
Research
- 8 to 10 grants of 2,400,000
- Use simulation to mirror, anticipate, or amplify
real situations with guided experiences in a
fully interactive way (e.g., mannequins are used
for teaching CPR)
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16PA-00-111
- AHRQ Health Services Research
- Primarily R01s
- R01 is a large research grant
- Large means over 100,000
- Special Emphasis Note describes current Agency
priorities
17Special Emphasis Note FY 2006
- Redesign and Evaluation of Patient Centered Care
for Chronically Ill - Coordination of care across settings
- Health education and patient self-management
- Strategies to reduce disparities
- Organizing care
- Implications for professional education and
training - Impact of strategies, structures, and practices
on access and clinical outcomes - Financial implications of care coordination
- Cost-effective health system improvements
- Pay for performance
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19PA-00-111
- AHRQ always encourages
- partnerships with private and public
organizations to facilitate development and
sharing of scientific knowledge and resources - cost-sharing mechanisms
- projects that will produce results within 2-3
years - results that can be integrated rapidly in
practice and policy.
20PAR-01-040
- AHRQ Small Research Grant Program
- Primarily R03s
- R03 is a small research grant
- Small means under 100,000
- Ideal for new investigators
- Special Emphasis Note applies
21PA-03-117
- AHRQ Grant Program for Large Conference Support
- R13 mechanism
- direct costs of more than 50,000 per year OR
- project period of longer than 1 year, but not
exceeding 5 years
22PA-03-117
- Intended to complement and promote AHRQ's core
research by providing a mechanism - to develop health services research agendas and
identify strategies for studying them - to discuss and develop consensus around
methodological and technical issues - to disseminate health services research
information and facilitate adoption of research
findings - to develop partnerships with stakeholder
organizations and build their capacity to
participate in research activities and use the
results of health services research.
23PA-06-074
- Small Grant Program for Conference Support
- Small conference grants are those with direct
costs of 50,000 or less over the project period.
- Applicants may request full or partial support
for conferences. (Requests for partial support
are encouraged.)
24PAR-06-118
- AHRQ Grants for Health Services Research
Dissertation
- Total direct costs awarded must not exceed
35,000 for the entire project period, which
should be a minimum of nine months and not to
exceed 17 months in duration
25PA-00-069
- Predoctoral Fellowship Awards for Minority
Students
- Up to five years of support for research training
leading to the Ph.D. or equivalent research degree
- New announcement due May 1, 2006
26Other PAs
- PA-00-010
- Mentored Clinical Scientist Development Award
- K08 mechanism
- See website for co-sponsored PAs
- Often co-funded with NIH
- Typically use R01, R03, etc. mechanisms
27FY 2007 -- Patient Safety
- FY 2007 Planning Level 84 million
- 35.2 million Ambulatory Patient Safety Program
(29.4 M HIT funds and 5.8 M in general PS
funds) - Patient Safety Quality Improvement Act
28Ambulatory Patient Safety Program
- Current public and private sector patient safety
programs have focused largely on care for
hospitalized patients - This investment will focus on ambulatory
settings. - Primary focus will be improving the safety and
safe use of medications. - Will use health information technology
29FY 2007Non-Patient Safety Research
- 17.1 million in new research grants
- These grants will continue research in our 10
portfolios of work with an increased focus on
knowledge translation.
30Applying for a Grant
- Application reviewed by study section
- Revise and resubmit application
- Application with low technical merit score (lower
is better) go to funding meeting where decision
to fund is made based on programmatic concerns.
31Submission Dates
- Mechanism Cycle 1 Cycle 2 Cycle 3
- R01, R13, Feb 1 June 1 Oct 1
- K08
- R03 Mar 24 July 24 Nov 24
- R36 Apr 10 Aug 10 Dec 10
See website for updates and further details.
32Study Sections
- Applications are scored
- 1.0-1.5 Outstanding1.5-2.0 Excellent2.0-2.5
Very Good2.5-3.5 Good3.5-5.0 Acceptable
- Applications are ranked
- Shows the relative position of each application's
score among all scores assigned by a study
section at its last three meetings.
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34Your Successful Application
- Leads to important research
- Fits well with AHRQs priorities
- Meets requirements of specific program
announcement - Rates high on scientific merit
- Will produce research that matters
-
35Application Fundamentals
- Plan Choose problem. Develop hypotheses, design,
project plan - Write concept paper
- Consult colleagues agency program staff
- Build a strong team Cover methods, topics, sites
- Present well Write a clear convincing
application - Revise and resubmit
361. Planning
- Scientific plan
- Literature, background
- Hypotheses
- Design aims (stages) and procedures for each
aim - Instrument development and pilots
- Research implementation plan including
contingency plans - Project plan
- Budget
- Access to sites and data
- Human subjects informed consent, protocols
- IRB approvals
- Institutional arrangements and approvals
371. Planning (Contd)
- Finding a research mechanism
- How much has already been done to address your
research question? - Do you have pilot data?
- What is the necessary timeframe?
- What are the needed resources?
382. Writing Concept Paper
- Main hypothesis or research questions
- State of the field
- Design
- Sample
- Design (e.g. cross-sectional, prospective, RCT,
case study) - Data gathering methods
- Statistical methods
- Fit with Agency/ support mechanism
- Distinctive competencies of investigator team
- Questions
393. Consulting Others
- Senior investigators and mentors -- at your
institution and elsewhere - Campus research office
- Peers
- Program officers
- Website and printed resources
- Potential co-funders
- Stakeholders, user groups
- Workshops
404. Team Building
- Grants experience
- Subject expertise
- Methodological expertise
- Professional expertise
- Links to research sites
- Team dynamics time commitments, leadership,
coordination - Stakeholder and user involvement
- Letters of cooperation
- Access to sites
- Dissemination plan
415. Presenting the Application
- State the distinctive contribution and relevance
to program announcement - Provide a tight scientific plan
- Be concrete define terms, give examples
- Use graphics for complex relations
- Provide measurement tools and findings from
pilots - Anticipate questions about design and methods
- Spell out project implementation, including
- Cooperating sites, researchers
- Data access
- Team members, contributions, coordination
- Timetable
- Products
425. Presenting (Contd)
- Writing tip
- Study section members and agency staff are busy
people, so - Make it easy for them to understand why your
application should be given a high score and be
generously funded!
436. Revise and Resubmit
- Expect criticism
- Respond to comments systematically and
non-defensively - Specify how you dealt with comments
- Be prepared to resubmit elsewhere or try another
idea at same agency
446. Revising (Contd)Responding to Comments
- Before... While the hypothesis is original, the
significance and ultimate impact in the health
care field are questionable. ..The application
is a useful academic exercise with limited
practical applications. .. There is a lack of
clinicians in the study..The need for proposed
methods development is not well justified. Why
would the setting studied be different from
other well-researched settings? - After This is a well-designed study to adapt
body of theory and methods to the field. The
investigators were extremely responsive to
initial review. In general, this is an
outstanding study from a strong, experienced team
of investigators, which includes knowledgeable
clinicians. The study fills an important
knowledge gap It is likely to produce important,
policy-relevant findingsThere is a need for a
series of examples of how the tool will be used.
The committee needs a clear sense of what the
researchers are doing and where they are going.
45AHRQ is Transitioning to Electronic Submission of
Applications
- The current PHS 398 application will be replaced
by the Standard Form (SF) 424 Research and
Related (RR) application.
- Details are available on the website
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47Help is Available
- Program Officers, such as myself, want to provide
you with assistance
- Staff contacts are listed on the website
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49Help is Available
Materials providing further information developed
by Michael Harrison, Ph.D. and colleagues
available at http//www.esi-bethesda.com/grantsm
anship/presentations.htm
My contact information Ryan Mutter 301-427-1415
rmutter_at_ahrq.gov rmutte1_at_umbc.edu