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...is the Fine Chemical business of International
Chemical Investors Group (ICIG)
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ICIG represents 15 operating companieswith
3,000 employees and sales of 600 mio
Profile

• International Chemical Investors is a privately
  held investment group focusing on mid-sized
  chemicals businesses, preferably subsidiaries of
  large corporations operating in competitive
  environments, which were considered non-core and
  acquired at low multiples
• Strengths Narrow focus on chemicals, well
  invested plants in favorable locations,
  international orientation, leading positions in
  niche markets, experienced employees trained in
  major chemical corporations, best practice across
  all activities
• Operating Companies 17
• Sales 650 million
• Employees approximately 3,000
• Locations 19 manufacturing plants, 11 in
  Germany, 3 in the United States, 2 in France, 1
  in Ireland, Italy and Poland in addition sales
  offices in Germany, the United States,
  Switzerland, Belgium, Italy, Spain, the United
  Kingdom and China
• Heritage of Operating Companies RAG / RÜTGERS,
  Akzo Nobel / Acordis, Albemarle, Cambrex,
  Clariant, Solvay, AstraZeneca, Mitsubishi

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ICIG is a long term investor exclusively
focussedon chemicals and chemical related
industries
Strategy

• Investments in chemicals or chemicals related
  industries only
• Long term holding approach, patient and
  knowledgeable investors
• Flexible and fast transaction structuring and
  closing ability
• Platform potential for additional add-on
  acquisitions preferred
• Standalone operations but best practice exchange
  across portfolio companies
• State of the art monitoring and control systems
• Administrative services unit (IT, accounting,
  insurance, credit etc.), providing services to
  group operating companies, if appropriate
• Attractive management and employee incentive
  programs

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ICIG can offer its customers the whole
pharmaceutical (and agrochemical) value chain
Fine Chemicals Oper-ations
Basic Chemicals
Fine Chemicals
Advanced Intermediates non-GMP GMP
Active Ingredients
Final Dosage Form
THANN, PORT DE BOUC (F)
CORK (IRE),
PLANKSTADT
ELGIN (US), TRISSINO (Italy) GRIESHEIM, HÖCHST,
MANNHEIM
CHENOVE (F)

• Final dosage form capacities at the Plankstadt
  site complete the elements of the pharmaceutical
  value chain within ICIG operating companies
• Extension of offered service range to existing
  customers (One-stop shopping)
• Sales to the pharmaceutical industry managed by
  Corden sales organisation

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ICIG offers Fine Chemicals under those brands...
Mannheim
Fine Chemicals, Thann
Trissino
Our Customers
Elgin
Frankfurt
Port-de Bouc
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WeylChem operates production plants in Germany
and US
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All facilities offer a broadrange of
capabilities for Custom Manufacturing
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ICIG Fine Chemicals Technologies and Product
Lines
Core Competencies
Support Reactions
Main product lines
Photochlorination Catalytic Oxidations Fluorinatio
n via Halex, HF or Electrochemical
Bromination Diazotization/Sandmeyer Grignard
Chemistry Ullmann coupling Allylations Enzymatic
Reductions
Alkylation/Acylation Acid chloride
formation Carbonylation Claisen
rearrangement Chlorination Diels Alder
reaction Esterification Friedel Crafts
reaction Fries rearrangement High pressure
hydrolyses Knoevenagel Michael addition Wittig
reaction Wurtz coupling and more
Benzyl chlorides Benzaldehydes Benzoyl
chlorides Carboxylic acids/esters/anhydrides Fluor
oaromatics Various organic bromides Grignard
reagents R-Mg-X Diphenyl ethers Allyl
Esters/Ethers Quinolines Acylation Products

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Key technologies Frankfurt-Höchst

• Side chain chlorination VP3

• Capacity 7,500 mt/a
• 4 Chlorination lines
• 2 Hydrolysis lines
• Various distillation units

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Key technologies Frankfurt-Griesheim

• Fluoroaromatics via Halex Exchange

Examples
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Key technologies Miteni-Trissino

• Benzotrifluorides

SIDE CHAIN PHOTOCHLORINATION
HALOGEN EXCHANGE
ANCILLARY TECHNOLOGIES
R1 None, Cl, F, COCl, etc.
R2 Cl,
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Key technologies Miteni-Trissino

• Perfluorinated derivatives

ELECTROCHEMICAL FLUORINATION

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Key technologies Mannheim

• Enzymatic Reduction from Ketones to chiral
  alcohols

• substrate concentration ? 10
• inexpensive enzyme
• complete and quick conversion in about 6-24 hours
• cost contribution of coenzyme lt 1 /kg product

OxI OxII substrate coupled coenzyme
regeneration OxI ? Ox II enzyme coupled
coenzyme regeneration
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Key technologies Mannheim

• Enzymatic reduction

(S)-3-Hydroxypyrrolidine
(S)-()-3-Hydroxytetrahydrofuran
(S)-3-Hydroxy-N-substituted pyrrolidines
(R)-4-Mercapto-2-pyrrolidone
(S)-ß-Hydroxy-? butyrolactone
(S)-4-Hydroxy-N-substituted-pyrrolidones
(S)-4-Hydroxy-2-pyrrolidone
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Elgin Key Technologies

• Grignard reaction products

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Thann/ Port de Bouc Typical Molecules
Monobromo.
a-Halogenated acid derivatives
Dibromo .. or mixed halogens
?-Halogenated acid derivatives

a,?-Dihalogenated acid derivatives
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Marketing and New Business Development Dr. John
C. Wetzel 1(803) 438 7762 john.wetzel_at_weylchem
.com Dr. Wolfgang Mueller 49 69 3800
2109 wolfgang.mueller_at_weylchem.com Dr.
Andrea Missio 39 0445 499560 andrea.missio.mi
teni.com