Most Frequent Systemic Infections

1
Most Frequent Systemic InfectionsInfants
IF-1
Decreased
Increased
Bronchitis
Conjunctivitis
Ear infection
Enterobiasis
Gastroenteritis
Gastroenteritis viral
Influenza
Laryngitis
Lower respiratory tract infection
Nasopharyngitis
Otitis externa
Otitis media
Pharyngitis
Pharyngitis streptococcal
Pneumonia
Respiratory tract infection
Rhinitis
Sinusitis
Tonsillitis
Tooth abscess
Tracheitis
Upper respiratory tract infection
Urinary tract infection
Viral infection
Pyrexia
-4
-2
0
2
4
Base as incidence density Elidel n 495 vehicle
n 193
Log Relative Risk (Elidel/vehicle) with 95 CI
2
Adjusted Incidence of Viral Skin
InfectionsElidel vs Topical Corticosteroids
Patients, Patients,
Elidel 1n 328 Topical corticosteroids n 330 P value
Any viral skin infection 7.0 8.9 .598
Herpes simplex 6.0 5.5 .855
Skin papilloma 0 2.0 .029
Herpes simplex ophthalmic 1.0 0.3 .400
Herpes zoster 0.5 0.7 .883
Herpes simplex dermatitis 0.7 0 .128
Molluscum contagiosum 0 0.7 .254
Long-term adult study B308. Log-rank test.
Adjusted incidence (Kaplan-Meier estimate) refers
to specific incidence at Month 12. Topical
corticosteroids (triamcinolone 0.1 cream /
hydrocortisone 1 cream).