Sphase Interphase

1
?????????????????????????

• ???????????????????????????????????????
• ?????????????? S-phase ??? Interphase
• ??????????? sister-chromatid
• ??? semiconservative

2
(No Transcript)
3
???????????????????

• DNA ???????????????????????? 2 nm.
• ?????? octamer histone core ?????? 2 ??? ????
  nucleosome ???????????????????????????? 11 nm.
• ???? histone H1 ??????? DNA linker
  ????????????????? 1 ????? 6 nucleosomes
  ????????????????????????? 30 nm.

4
Nucleosome
5
Interphase chromatin
6
(No Transcript)
7
Prop hase
8
Chromosome
Satellite Nucleolar Organizzer Region (NOR) short
arm centromere long arm
9
???????? CHROMOSOME

• ??????????????
• AUTOSOME
• SEX CHROMOSOME

10
???????? CHROMOSOME

• ???????????????????????(centromere)
• Jtelocentric Jsubmetacentric
  Jacrocentric Jmetacentric

11
(No Transcript)
12
Acentric ftagment
???????????????????????????????
Dicentric chromosome
???????????????? ????????????????????????????????
13
????????????? Chromosome number

• ???????????????????????????????????? ???????
• ???????????????????????????????? 2 ??? ????????
  diploid (2n) ???????????????????(sperm)
  ????????????????????(ovum)
• ????????????????????????????? (gamete)???????????
  ?????? haploid (n)

14
?????????????

• Human (Homo sapiens) 46
• Garden pea ( Pisum sativum) 14
• Fruit fly (Drosophila melanogaster) 8
• House mouse ( Mus musculus) 40
• Round worm (Ascaris sp.) 2

15
?????????????

• Pigeon (Columba livia) 80
• Boa constrictor(Constrictor constrictor) 14
• Cricket (Gryllus domesticus) 22
• Lily ( Lilium longiflorum) 24
• Indian fern(Opbioglossum reticulatum) 1,260

16
??????????????? 2 ??????? 2544???????????
?????????????
???????
17
??? DNA ???????????????????????? ???????????
mRNA ??????????? DNA ?????????????????????????????
?
3
5
3
5
Sense strand