Infected mare passes EHV-1 infection to their foal

1
Infected mare passes EHV-1 infection to their foal
Target for Vaccination limiting viral infection
of foal from shedding by infected mares
Target for Vaccination limiting transmission from
infected foals to pregnant mares
Infected foal sheds the virus acting as a source
of infection for other pregnant mares
2
EHV-1
virus infects leukocytes and causes a
cell-associated viremia
virus infected epithelial cell
virus spreads to local lymph nodes
Virus spreads to and infects endothelial cells
lining blood vessels leading to vasculitis,
thrombosis and ischemia
3
Reactivation of latent viral infection leading to
abortion, infection of foal or spread to other
mares