Andrew Newbigging

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• Andrew Newbigging
• Managing Director

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Agenda

• Review of the past year
• Product development
• Future strategy

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Review MACRO

• MACRO 3.0
• released in July 2003
• first study live in August 2003
• most customers have migrated or are in process of
  migrating to 3.0
• MACRO studies
• gt 65 studies
• gt 70,000 patients
• gt 400 sites in 35 countries

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Review MACRO
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Review MACRO

• New customers
• Institut Curie
• Institut Bergonie
• Diabetes Trial Unit, Oxford
• Centre Alexis Vautrin
• Organon ( Quintiles)

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Review Services
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Review Services
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Review Services
Secure Hosting Facility
Sites
Oracle Clinical database Study CDMS Data
Repository Back-end discrepancy management
Clinical Gateway Conduit to Oracle Clinical
Database Mapping tool for Macro
MACRO Remote Data capture of site data.
Front-end discrepancy management
24x7 help desk
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Review Clinical Gateway

• Integrates MACRO with Oracle Clinical
• Co-development with Roche
• Version 2.0 completed
• InferMed has Oracle Clinical in-house for future
  development and support of Clinical Gateway

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Review VTRACK

• Volunteer management for clinical pharmacology
  units
• Live at 2 sites
• New version in testing

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Review Design-a-Trial

• Computer assisted protocol design
• Statistics support
• Draft protocol and ethics document
• Trial outline design
• Evaluation feedback from 20 users

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Review Design-a-Trial
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Review AREZZO

• Pharma-sponsored international guidelines
• Pfizer
• Prospect Post-operative pain management
• www.postoppain.org
• Roche
• Retrogram HIV Anti-retroviral combination
  therapy
• www.retrogram.com
• Roche
• Orama Renal anaemia management

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Review AREZZO

• Healthcare
• Eclipsys
• Top 3 US Electronic Patient Record supplier
• Integrate AREZZO for intelligent documentation
• UK NHS
• PROforma language, as used in AREZZO, being
  evaluated for possible UK standard
• British Medical Journal
• Clinical Evidence Interactive
• www.infermed.com/ce-i
• (username user / password user)

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Product development

• MACRO 3.0
• No new functionality to be added to core
• New modules may be added
• Automatic software update
• SOAP XML API
• Platform support
• Oracle 10G
• Windows 2003 server
• CITRIX ?
• Security review
• Performance

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Product development

• MACRO 3.0 Desktop edition
• Beta review
• Database size limit
• No remote data entry
• Low cost

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Product development

• TENALEA
• EC funded project starting in June 2004
• Randomisation service
• Integrated with MACRO
• Co-ordinated by NCI, Amsterdam
• Some MACRO users are already participating
• Others can join in

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Product development

• MACRO 3.1
• clinical coding (MEDDRA)
• long text fields
• horizontal option buttons
• multimedia questions in WWW module
• release timescale to be reviewed

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Product development

• MACRO 3.2
• Features under consideration
• eForm/question level security
• Study level security in study definition module
• New validation type to create discrepancies
• Derivable labels
• Optional visits

• MACRO 4.0
• Features under consideration
• multi-user study definition
• contact management
• document management
• scheduling
• materials and inventory
• payment

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Product development

• Process
• Funded enhancements
• InferMed initiated
• Maintenance
• Percentage of overall maintenance revenue goes
  towards new development
• Weighted voting on priorities
• Weighting proportional to annual maintenance
  payment

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Future strategy


Technology
Architecture
MICROSOFT COM
USER INTERFACE
LINUX .NET ?
MODULES
MICROSOFT .NET
CORE
MICROSOFT LONGHORN ?
INTEGRATION

Services
Customers
InferMed
Pharma
CRO
Service Partners
Service Partners
Academic Not for profit
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Thank you