CPAT3101 Microscopy Practical

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CPAT3101 Microscopy Practical Neoplasia
1 Benign Tumours
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Fundus
Fibroid
Cervix
Leiomyomas (fibroids) in uterus
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Normal Uterine wall
Spindle shaped smooth muscle cells
Ordered alignment parallel to uterine surface
Arteriole
Venule
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Border between Leiomyoma and Uterine Wall
Normal uterine wall with ordered parallel fibres
Leiomyoma with whorled cut surface
Well demarcated edge of benign tumour
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Leiomyoma tumour cells
Bundles
- Longitundinal
- Transverse
Randomly arranged bundles of spindle-shaped
tumour cells - whorled appearance
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Special Stain for smooth muscle and fibroblasts
Leiomyoma
Uterine wall
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Rectum
Anus
Benign Colonic Polyps
- pedunculated (stalk) - not ulcerated
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Endoscopic view of Colonic Polyp
Interior of colon
Polyp
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Normal Colonic Epithelium
Mucosa - crypts - goblet cells
Lymphoid tissue
Submucosa
Muscularis mucosae
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Junction between colonic polyp and mucosa
Fern-like structure of colonic polyp
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Colonic Polyp
Neoplastic epithelial cells - pleomorphism,
heaped up
Fibrovascular core