Embryology

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Week 1
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Morula
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Blastocyst
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Week 2
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Amniotic Egg

• 3 primary membranes
• Amnion

blastodisk
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Week 3

• Primitive streak
• 3 primary germ layers
• Notochord formation
• Neurulation
• Differentiation

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Primitive Streak 3 Germ Layers

• Primitive streak (day 15)
• Tail to head
• Cells migrate in/downward
• Endoderm
• Mesoderm (day 16)
• Ectoderm
• Differentiation

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Notochord Formation

• Primitive node
• Defines body axis
• Starts at future tail region day 16
• Reaches future head region day 18

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Neurulation

• Neural groove
• Neural tube
• Brain
• Spinal chord
• Neural crest cells

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Mesodermal Differentiation

• Forms 3 distinct regions
• Paraxial mesoderm
• Somites

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Mesodermal Differentiation

• Forms 3 distinct regions
• Paraxial mesoderm
• Intermediate mesoderm

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Mesodermal Differentiation

• Forms 3 distinct regions
• Paraxial mesoderm
• Intermediate mesoderm
• Lateral plate mesoderm
• Somatic mesoderm
• Splanchnic mesoderm

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Week 4

• Folding
• Endoderm
• Gut tube bladder
• Ectoderm
• Brain, spinal chord, epidermis
• Mesoderm
• Everything else in between
• Coeloms

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Weeks 5 8
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