NIH CTSA Awards: Home for Clinical and Translational Science

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NIH CTSA Awards Home for Clinical and
Translational Science
NIH
Clinical Research Ethics
Trial Design
Advanced Degree-Granting Programs
Biomedical Informatics
CTSA HOME
Industry
Participant Community Involvement
Clinical Resources
Other Institutions
Biostatistics
Regulatory Support
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Building a National CTSA Consortium
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Impact of 12 Awards in 2006

• The 2006 awards subsumed
• 3 pediatric and 16 adult GCRCs
• 3 RM-K12
• 3 RM-T32s,
• 4 NCRR-K12
• 9 K30s
• And created 51 T and 91 K positions
• Awards in FY2007 will subsume a comparable number
  of RM and RR awards.

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Organization of CTSAs

• Each CTSA has to include an institution that can
  award higher degrees in clinical research
• Each CTSA has to include research education and
  career development activities
• Awards are made as cooperative agreements and
  awardees agree to work together
• CTSAs send representatives to the governance
  structures, including steering committees and
  workgroups

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Governance for cooperative agreement

• Committees will work to develop, adopt, and
  implement solutions to impediments to
  collaborative clinical and translational
  research. CTSA institutions must be committed to
  active collaborative participation at the
  national level
• Steering Committees are the forum for consortium
  management
• NIH sends science advisors drawn from across
  the NIH to provide scientific input to Steering
  Committees
• NCRR sends project scientists, program officers
  and grants management specialists to each CTSA

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CTSA Steering Committees and Workgroups

• Embody the expertise of the Consortium
• Provide a forum for dialogue with the NIH
• Identify needs, goals and priorities
• Serve as a platform to adopt common standards
• Have deliverables and timetables

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Progress with First Awards

• Secured commitment to collaborative effort
• Rapid implementation of pilot project programs
• Rapid implementation of career development
  programs
• Active IRB projects alternative models and
  pediatric harmonization
• Visit CTSAWeb.org to follow progress

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Source of awards receiving CTSA support
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Community Engagement Milestones, July 2007

• Established Community Based Advisory Boards
• Performed Community Engagement Needs Assessments
• Established/Leveraged Partnerships for Funding
• Developed Relevant trans-CTSA educational
  curriculum
• Developed Evaluation Outcomes/metrics for
  Community Engagement Research
• Developed a Forum for Sharing Resources/Instrument
  s

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Pediatric Oversight Committee

• Arranged webconference for all participating
  sites at which IRB members will discuss case
  scenarios
• POC members will post a list of useful networks
  and consortia on the CTSA web site
• POC members will review this process periodically
  to determine its usefulness
• Each POC member will review the pediatric
  membership on their local K awards committees,
  and report back prior to the next call.

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Informatics Steering Committee

• Identify additional resources to maintain
  listservs and additional methods for workgroup
  communications
• Develop a Wiki to post documents and other
  materials.
• Hold a monthly phone call to include one director
  from each center and the leads from the working
  groups
• Write a white paper detailing the differences
  between informatics and IT. Mike Becich is the
  lead on this
• Discussion will continue on possible alignment
  with caBIG and interaction with ONC
• Hold a webinar on BIRN (Biomedical Informatics
  Resource Network) in July to disseminate tools.

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Research Education Steering Committee

• Address transitioning from K to R support the
  most vulnerable point for many CTSA members.
• Agree on duration of K12 to K23 training
• Plan a national meeting that could be attended by
  TL1 trainees and all K scholars
• Identify sharable web accessible educational
  tools
• Plan meeting to address curricula for clinical
  research

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Options CTSA 1 year program CTSA MD PhD/MS
program MSTP program to MD PhD
Options Academic track Third year electives
Medical student years
Intern
Resident
Options Categorical T32 CTSA
K12. Categorical K23
Clinical
Research
1st academic appointment
R01
Very vulnerable
Fellowship
Vulnerable
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Further rounds of CTSAs

• 2008 will differ in
• Allowing for multiple PIs
• Compliance with Pediatric Requirement of NIH
  Reform Act.
• Applications due November 7, 2007
• Up to 8 awards expected in June 2008
• 2009 awards
• Submission dates are June 17 and October 21, 2008

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See www.ctsaweb.org