Integrating Biological and Medical Knowledge

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Integrating Biological and Medical Knowledge

• Bradley Hemminger Ph.D.
• School of Information and Library Science,
  University of North Carolina, Chapel Hill
• http//ils.unc.edu/bioinfo

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Grand Challenge

• Integration of Knowledge
• Requires framework for sharing of knowledge
  across disciplines (large scale ontologies such
  as GO, small scale such as MIAME)
• Requires standards to implement common frameworks
  (metadata within ontologies)
• Requires infrastructure (communications,
  databases, standards) to support universal
  exchange

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Work at UNC in School of Information and Library
Science

• Developing ontology/metadata frameworks to
  support exchange of information in biology and
  medicine (for example PROMIS for the
  standardization and exchange of proteomics
  experiment results)

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Contd

• Linking knowledge found in experiments, journal
  articles, books, analyses so that correlations
  are easily uncovered, and new inferences deduced
  (NeoRef)
• Archival and Preservation issues for
  bioinformaticshow to store and maintain
  experimental information (NeoRef digital
  libraries)
• Novel methods for the common representation of
  all biomedical information (Ultrastructure).

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PROMIS SCHEMA
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Concept Map
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