Epidemiology of Diabetes Mellitus(DM) in Siberia

1
Epidemiology of Diabetes Mellitus(DM) in Siberia

• Eugene Shubnikov, MD
• Center for Endocrinology SibDiab
• Novosibirsk, Russia

readings
2
Objectives

• To Outline the Incidence of Type 1 DM among
  Children in Novosibirsk Area, Russia
• To Describe the Prevalence of DM and Impaired
  Glucose Tolerance (IGT) among Adult Population of
  Novosibirsk City, Russia.
• To Discuss the Prevalence of DM among Native
  Polulation of Chukotka Pepublic of Russia.

3
Map of Russia
Chukotka
SIBERIA
Moscow
Novosibirsk
4
Siberian IDDM Registry

• Case Identification is Based on
• 1. Review of Hospital Records at Novosibirsk
  Citys Hospitals
• 2. Review of Out-Patient Clinics Data at
  Novosibirsk City

5
Siberian IDDM Registry

• Consists of
• Novosibirsk Area IDDM Registry
• Novosibirsk City IDDM Registry

6
Novosibirsk District
Novosibirsk area-178 300 sq.km.
Novosibirsk City 477 sq.
km.
7
Incidence of IDDM per 100000 Children before Age
of 15 for 1980-1996
8
Incidence of IDDM by Age Groups
9
Time Trends in IDDM Incidence
10
Family History Information

• From 715 Cases Diagnosed before Age 15, our Data
  Base Includes Information on
• 19 Families where Child and One Parent Suffer
  from IDDM
• 10 Families where Two Siblings Suffer from IDDM

11
Hypothesis

• Taking into Account Small Number of Multiplex
  Families, the Increase in Risk at Puberty and
  Increasing IDDM Incidence, we Suppose that Some
  Unknown Casual Agents are Playing an Important
  Role at IDDM Pattern in Siberia

12
Map of Russia
Novosibirsk
2
1
13
Prevalence of DM According to Screening Data

• First Standardized Study of a Representative
  Sample of Russian Men and Women 25-64 years in
  Novosibirsk City in the Frame of WHO MONICA
  Project.
• 1985 WHO Criteria for Diagnosis of DM and IGT
• Data was Compared to DM Registry Data at the same
  Area

14
The Prevalence Estimates for IGT and DM in Per
Cent
15
The Prevalence Estimates for Previously
Diagnosed and New Cases of DM
16
CHUKOTKA
ALASKA
17
Number of DM Patients among Chukotka Native
Population
Number of Cases
Years
18

LORINO
ANRAKINNOT
NEW CHAPLINO
SIRENIKI
19
Prevalence of DM among Chukotka Natives According
to Screening Data

• We Confirmed just One Case of DM in an Eskimo
  Woman(Diagnosed Previously) during the Screening,
  that was 0,5 of Examined Female Population.
• There were no DM Cases in Examined Male
  Population.

20
The Age Distribution of IGT Prevalence among
Chukotka Natives
21
Owerweigh among Chukotka Natives (Screening Data)

• Body Mass Index (BMI) was Greater than 29 among
  8,3 of Men and 29,4 of Women.
• There were 17,9 of Men with BMI Greater than 27
  and 55,6 Women with BMI Greater than 25.

22
Changes in Diet among Chukotka Native Adults
during 10 years
In per cent ()
Farida R.Mamleeva et al., 1996
23
Conclusion

• According to Our Investigations, the Incidence
  and Prevalence of DM in Siberia are Relatively
  low, Compare to other European and World
  Populations.
• We have Revealed the Increasing of DM Incidence
  and Prevalence at all Siberian Regions which
  Reflects Global DMs Tendency.